Doxil
National Institutes of Health
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PurposeOur recent studies show specific localization of long-circulating liposomes (LCL) within the endosomal/lysosomal…
Liposomes, modified with monoclonal antibodies, are suitable carriers for targeted delivery of chemotherapeutic drugs into brain…
Objective: A phase I/II study of Doxil® combined with whole abdomen hyperthermia was conducted in patients with refractory…
The application of tumor necrosis factor‐α (TNF) for the treatment of solid tumors is limited by its severe, life‐threatening…
The stability and biological behavior of an in vitro system of doxorubicin (DXR) entrapped in NK911, polymer micelles, was…
Pegylated-liposomal doxorubicin (Doxil™) is a form of liposomal doxorubicin in which the liposomes are coated with methoxypoly…
It has previously been demonstrated in the setting of an isolated limb perfusion that application of high‐dose TNF‐α in…
New therapies are needed for patients with advanced ovarian cancer who relapse after initial treatment with platinum and/or…
Twenty-four patients with pleural mesotheliomareceived 50 mg/m2 of Doxil® every four weeks.At follow-up, the disease had…