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Dexetimide

Known as: dextro-Benzetimide, (3,4'-Bipiperidine)-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, (S)-, dextro Benzetimide 
A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
National Institutes of Health

Papers overview

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2004
2004
Decreased muscarinic receptor binding has been suggested in single-photon emission tomography (SPET) studies of Alzheimer's… 
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1998
1998
Like amphetamine, scopolamine produces locomotor stereotypy (repetitive routes of locomotion) in an open field. To determine… 
Highly Cited
1988
Highly Cited
1988
Dexetimide (Fig. 1a), a potent muscarinic cholinergic receptor antagonist, and levetimide (Fig. 1b), its pharmacologically… 
Highly Cited
1988
Highly Cited
1988
Summary Intracellular recordings were made from the large monopolar cells (LMCs), which are the cells postsynaptic to… 
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1985
1985
In this report we characterize muscarinic cholinergic receptor on embryonic cells. We established dose-response curves by… 
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Highly Cited
1983
Highly Cited
1983
Calf forebrain homogenates contain 2.8 pM muscarinic acetylcholine receptors per mg of protein. [3H]Antagonist saturation binding… 
Highly Cited
1979
Highly Cited
1979
A binding assay for muscarinic cholinergic receptors has been developed using labelled dexetimide as ligand and a filtration… 
1979
1979
Abstract— [3H]Dexetimide specifically labels brain muscarinic receptors in vivo. After i.v. injection of labelled drug into rats… 
1973
1973
Abstract Binding of the anticholinergic agent 3 H-dexetimide, the active isomer of (±)-benzetimide, to subcellular fractions of… 
1971
1971
THE pharmacological activity of (±) benzetimide (Fig. 1) ((±)-1-benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)-piperidine HCl), a…