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Dexetimide
Known as:
dextro-Benzetimide
, (3,4'-Bipiperidine)-2,6-dione, 3-phenyl-1'-(phenylmethyl)-, (S)-
, dextro Benzetimide
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A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
National Institutes of Health
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Related topics
Related topics
17 relations
Narrower (6)
4-bromodexetimide
4-iododexetimide
N-methyl-4-iododexetimide
Spasmentral
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Broader (3)
Antiparkinson Agents
Muscarinic Antagonists
Parasympatholytics
Benzetimide
In Blood
agonists
analogs & derivatives
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1992
Highly Cited
1992
Activation of T84 cell chloride channels by carbachol involves a phosphoinositide-coupled muscarinic M3 receptor.
K. Dickinson
,
R. Frizzell
,
M. Sekar
European Journal of Pharmacology
1992
Corpus ID: 23647160
1989
1989
In vivo cystometrogram studies in urethane-anesthetized and conscious guinea pigs.
J. Peterson
,
R. Hanson
,
L. Noronha-Blob
Journal of Pharmacological Methods
1989
Corpus ID: 36403053
1987
1987
[3H]AF-DX 116 labels subsets of muscarinic cholinergic receptors in rat brain and heart.
J. Wang
,
W. Roeske
,
K. Gulya
,
W. Wang
,
H. Yamamura
Life Science
1987
Corpus ID: 19988941
Highly Cited
1985
Highly Cited
1985
The muscarinic receptor of chick embryo cells: correlation between ligand binding and calcium mobilization
G. Oettling
,
H. Schmidt
,
U. Drews
Journal of Cell Biology
1985
Corpus ID: 70135
In this report we characterize muscarinic cholinergic receptor on embryonic cells. We established dose-response curves by…
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1984
1984
Characterization of muscarinic cholinergic receptors on rat pancreatic acini by N-[3H]methylscopolamine binding. Their relationship with calcium 45 efflux and amylase secretion.
J. Dehaye
,
J. Winand
,
P. Poloczek
,
J. Christophe
Journal of Biological Chemistry
1984
Corpus ID: 12881428
1984
1984
Differentiation between ligand trapping into intact cells and binding on muscarinic receptors.
A. Gossuin
,
J. Maloteaux
,
A. Trouet
,
P. Laduron
Biochimica et Biophysica Acta
1984
Corpus ID: 37643222
Highly Cited
1981
Highly Cited
1981
In vivo characterization of myocardium muscarinic receptors by positron emission tomography.
M. Maziére
,
D. Comar
,
J. Godot
,
P. Collard
,
C. Cepeda
,
R. Naquet
Life Science
1981
Corpus ID: 20033504
Highly Cited
1980
Highly Cited
1980
Muscarinic receptor binding in rat brain using the agonist, [3H]cis methyldioxolane.
F. Ehlert
,
Y. Dumont
,
W. Roeske
,
H. Yamamura
Life Science
1980
Corpus ID: 38822945
Highly Cited
1979
Highly Cited
1979
STEREOSPECIFIC IN VlTRO BINDING OF [3H]DEXETIMIDE TO BRAIN MUSCARINIC RECEPTORS
P. Laduron
,
M. Ver Wimp
,
J. Leysen
Journal of Neurochemistry
1979
Corpus ID: 45499488
A binding assay for muscarinic cholinergic receptors has been developed using labelled dexetimide as ligand and a filtration…
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1976
1976
Alteration in the action of cholinergic and anti cholinergic drugs after chronic haloperidol: indirect evidence for cholinergic hyposensitivity.
G. Gianutsos
,
H. Lal
Life Science
1976
Corpus ID: 44363607
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