Dexetimide

Decreased muscarinic receptor binding has been suggested in single-photon emission tomography (SPET) studies of Alzheimer's… Expand

Dexetimide (Fig. 1a), a potent muscarinic cholinergic receptor antagonist, and levetimide (Fig. 1b), its pharmacologically… Expand

Summary Intracellular recordings were made from the large monopolar cells (LMCs), which are the cells postsynaptic to… Expand

In this report we characterize muscarinic cholinergic receptor on embryonic cells. We established dose-response curves by… Expand

Calf forebrain homogenates contain 2.8 pM muscarinic acetylcholine receptors per mg of protein. [3H]Antagonist saturation binding… Expand

Abstract The feasibility of studying myocardium muscarinic receptors, non invasively, in a “live” being can be demonstrated using… Expand

A binding assay for muscarinic cholinergic receptors has been developed using labelled dexetimide as ligand and a filtration… Expand

Abstract— [3H]Dexetimide specifically labels brain muscarinic receptors in vivo. After i.v. injection of labelled drug into rats… Expand

Abstract Binding of the anticholinergic agent 3 H-dexetimide, the active isomer of (±)-benzetimide, to subcellular fractions of… Expand

THE pharmacological activity of (±) benzetimide (Fig. 1) ((±)-1-benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)-piperidine HCl), a… Expand