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Benzetimide

 
National Institutes of Health

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2008
2008
The synthesis and evaluation of benzetimide derivatives showing potent CXCR3 antagonism are described. Optimization of the… Expand
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2004
2004
SummaryThe peripheral and central anticholinergic properties of benzetimide (R 4929) and a series of 22 other atropine-like drugs… Expand
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1988
1988
Specific 3H-1-quinuclidinylbenzilate (3H-1-QNB) binding to rat cochlea homogenates occurs to a homogeneous class of binding sites… Expand
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1986
1986
(-)-[3H]Quinuclidinyl benzilate (QNB) binding to muscarinic receptors on intact mouse pituitary tumor cells (AtT-20/D16-16) was… Expand
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1985
1985
The muscarinic antagonist L-[3H]quinuclidinyl benzilate (L-[3H]QNB) binds with a high affinity (Kd = 0.77 nM) to a single… Expand
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Highly Cited
1981
Highly Cited
1981
Abstract The feasibility of studying myocardium muscarinic receptors, non invasively, in a “live” being can be demonstrated using… Expand
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Highly Cited
1980
Highly Cited
1980
Abstract Muscarinic receptor binding was measured in rat forebrain preparations using the muscarinic agonist, [ 3 H]cis… Expand
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1980
1980
The tritiated muscarinic cholinergic antagonist quinuclidinyl benzilate, [3H]QNB, was used as a direct probe for the detection… Expand
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1976
1976
1 Benzetimide, possessing two stable enantiomers, dexetimide and levetimide, has been investigated in guinea‐pig atria with… Expand
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1971
1971
THE pharmacological activity of (±) benzetimide (Fig. 1) ((±)-1-benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)-piperidine HCl), a… Expand
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