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Benzetimide

National Institutes of Health

Papers overview

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2008
2008
The synthesis and evaluation of benzetimide derivatives showing potent CXCR3 antagonism are described. Optimization of the… Expand
2004
2004
SummaryThe peripheral and central anticholinergic properties of benzetimide (R 4929) and a series of 22 other atropine-like drugs… Expand
1988
1988
Specific 3H-1-quinuclidinylbenzilate (3H-1-QNB) binding to rat cochlea homogenates occurs to a homogeneous class of binding sites… Expand
1986
1986
(-)-[3H]Quinuclidinyl benzilate (QNB) binding to muscarinic receptors on intact mouse pituitary tumor cells (AtT-20/D16-16) was… Expand
1985
1985
The muscarinic antagonist L-[3H]quinuclidinyl benzilate (L-[3H]QNB) binds with a high affinity (Kd = 0.77 nM) to a single… Expand
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Highly Cited
1981
Highly Cited
1981
Abstract The feasibility of studying myocardium muscarinic receptors, non invasively, in a “live” being can be demonstrated using… Expand
Highly Cited
1980
Highly Cited
1980
Abstract Muscarinic receptor binding was measured in rat forebrain preparations using the muscarinic agonist, [ 3 H]cis… Expand
1980
1980
The tritiated muscarinic cholinergic antagonist quinuclidinyl benzilate, [3H]QNB, was used as a direct probe for the detection… Expand
1976
1976
1 Benzetimide, possessing two stable enantiomers, dexetimide and levetimide, has been investigated in guinea‐pig atria with… Expand
1971
1971
THE pharmacological activity of (±) benzetimide (Fig. 1) ((±)-1-benzyl-4-(2,6-dioxo-3-phenyl-3-piperidyl)-piperidine HCl), a… Expand