Deoxyribonuclease I

Known as: DNase, Pancreatic, Deoxyribonuclease I [Chemical/Ingredient], Thymonuclease 
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide… (More)

Topic mentions per year

Topic mentions per year

1951-2018
020040019512017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Genome-wide association studies have identified many noncoding variants associated with common diseases and traits. We show that… (More)
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Highly Cited
2006
Highly Cited
2006
The TRANSFAC database on transcription factors, their binding sites, nucleotide distribution matrices and regulated genes as well… (More)
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Highly Cited
2001
Highly Cited
2001
Nucleosomal fragmentation of DNA is a hallmark of apoptosis (programmed cell death), and results from the activation of nucleases… (More)
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Highly Cited
2000
Highly Cited
2000
Many bacterial pathogens encode a multisubunit toxin, termed cytolethal distending toxin (CDT), that induces cell cycle arrest… (More)
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Highly Cited
1998
Highly Cited
1998
The homeostasis of animals is regulated not only by the growth and differentiation of cells, but also by cell death through a… (More)
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNF alpha) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the… (More)
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Highly Cited
1992
Highly Cited
1992
We have identified a 50-nucleotide enhancer from the human erythropoietin gene 3'-flanking sequence which can mediate a sevenfold… (More)
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Highly Cited
1990
Highly Cited
1990
The atomic models of the complex between rabbit skeletal muscle actin and bovine pancreatic deoxyribonuclease I both in the ATP… (More)
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Highly Cited
1988
Highly Cited
1988
Specific, end-labeled DNA fragments can be simply and rapidly prepared using the polymerase chain reaction (PCR). Such fragments… (More)
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Highly Cited
1974
Highly Cited
1974
Various tissues and cells in culture contain a specific inhibitor of DNase I (EC 3.1.4.5). In this paper evidence is presented… (More)
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