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Deoxyribonuclease I

Known as: DNase, Pancreatic, Deoxyribonuclease I [Chemical/Ingredient], Thymonuclease 
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide… 
National Institutes of Health

Related topics

Related topics

16 relations
DNASE1 geneIn BloodNickaseProcess of secretion

Broader (2)

Deoxyribonucleasesendodeoxyribonuclease

Narrower (1)

Dornase Alfa

Papers overview

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Highly Cited
2001
Highly Cited
2001
The Absence of Oligonucleosomal DNA Fragmentation during Apoptosis of IMR-5 Neuroblastoma Cells
Caspase-activated DNase is responsible for the oligonucleosomal DNA degradation during apoptosis. DNA degradation is thought to… 
Highly Cited
1994
Highly Cited
1994
Detection of epidermal growth factor receptor mRNA in tissue sections from biopsy specimens using in situ polymerase chain reaction.
Human epidermal growth factor (EGF) receptor mRNA was detected in cryopreserved tissue sections adherent to whole glass slides… 
Highly Cited
1993
Highly Cited
1993
In vivo and in vitro footprinting of a light-regulated promoter in the cyanobacterium Fremyella diplosiphon
Certain filamentous cyanobacteria, such as Fremyella diplosiphon, modulate the components of their light-harvesting complexes… 
Highly Cited
1989
Highly Cited
1989
Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor.
An activity (designated BTF1Y) in extracts of Saccharomyces cerevisiae can substitute for the human TATA box-binding factor BTF1… 
Highly Cited
1979
Highly Cited
1979
Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters.
Cyclic AMP (cAMP) and its receptor protein (CRP) have a dual role in the regulation of the two promoters that control the… 
Highly Cited
1977
Highly Cited
1977
Failure to detect circulating DNA--anti-DNA complexes by four radioimmunological methods in patients with systemic lupus erythematosus.
The presence of DNA-anti-DNA complexes in sera from patients with systemic lupus erythematosus (SLE) was investigated by two new… 
Highly Cited
1976
Highly Cited
1976
Nonrandom nature of in vivo methylation of dimethylnitrosamine and the subsequent removal of methylated products from rat liver chromatin DNA.
This investigation was designed to study whether methylation of liver chromatin DNA by dimethylnitrosamine (DMN) and the… 
Highly Cited
1976
Highly Cited
1976
Variations of DNA polymerase-alpha and -beta during prolonged stimulation of human lymphocytes.
Stimulation of human lymphocytes with phytohemagglutinin is known to induce an increase in overall DNA polymerase activity (DNA… 
Highly Cited
1973
Highly Cited
1973
DNA polymerases I and II in regenerating rat liver and Morris hepatomas.
Two nonmitochondrial forms of DNA polymerase are demonstrated in regenerating rat liver and Morris hepatomas 7777, 7800, and… 
Highly Cited
1968
Highly Cited
1968
The local nature of immunity in tuberculosis, illustrated histochemically in dermal BCG lesions.
Dermal BCG lesions and the subsequently developing cellular immunity and allergy were evaluated periodically in rabbits with… 
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