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Deoxyribonuclease I

Known as: DNase, Pancreatic, Deoxyribonuclease I [Chemical/Ingredient], Thymonuclease 
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide… 
National Institutes of Health

Related topics

Related topics

16 relations
DNASE1 geneIn BloodNickaseProcess of secretion

Broader (2)

Deoxyribonucleasesendodeoxyribonuclease

Narrower (1)

Dornase Alfa

Papers overview

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Highly Cited
1999
Highly Cited
1999
OxyR and SoxRS Regulation offur
ABSTRACT The cytotoxic effects of reactive oxygen species are largely mediated by iron. Hydrogen peroxide reacts with iron to… 
Highly Cited
1996
Highly Cited
1996
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
We describe the identification and characterization of a conserved downstream basal promoter element that is present in a subset… 
Highly Cited
1993
Highly Cited
1993
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).
Cell death by apoptosis occurs in a wide range of physiological events including repertoire selection of lymphocytes and during… 
Highly Cited
1986
Highly Cited
1986
The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the ‘termination’ codon, TGA.
Glutathione peroxidase (GSHPx) is an important selenium‐containing enzyme which protects cells from peroxide damage and also has… 
Highly Cited
1985
Highly Cited
1985
The "beta-like-globin" gene domain in human erythroid cells.
We have mapped the distribution of the major and minor DNase I-hypersensitive sites in the human "beta-like-globin" gene domain… 
Highly Cited
1985
Highly Cited
1985
Fibrillarin: a new protein of the nucleolus identified by autoimmune sera
Autoimmune serum from a patient with scleroderma was shown by indirect immunofluorescence to label nucleoli in a variety of cells… 
Highly Cited
1977
Highly Cited
1977
Nuclear matrix: isolation and characterization of a framework structure from rat liver nuclei
A nuclear framework structure termed the nuclear matrix has been isolated and characterized. This matrix forms the major residual… 
Highly Cited
1974
Highly Cited
1974
Actin is the naturally occurring inhibitor of deoxyribonuclease I.
Various tissues and cells in culture contain a specific inhibitor of DNase I (EC 3.1.4.5). In this paper evidence is presented… 
Highly Cited
1973
Highly Cited
1973
DNA Polymerase Associated with Human Hepatitis B Antigen
DNA polymerase activity was detected in each of eight preparations of concentrated human hepatitis B antigen (HBAg) rich in Dane… 
Highly Cited
1965
Highly Cited
1965
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.
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