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A novel virus in swine is closely related to the human hepatitis E virus.
TLDR
The discovery of swine HEV not only has implications for HEV vaccine development, diagnosis, and biology, but also raises a potential public health concern for zoonosis or xenozoonosis following xenotransplantation with pig organs.
An African primate lentivirus (SIVsmclosely related to HIV-2
TLDR
SIVsm has infected macaques in captivity and humans in West Africa and evolved as SIVmac and HIV-2, respectively, according to molecularly cloned and sequenced SIVsm.
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.
TLDR
Assays of ten blood transfusions in the United States that resulted in chronic NANBH revealed that there was at least one positive blood donor in nine of these cases and that all ten recipients seroconverted during their illnesses.
Hepatitis E virus
TLDR
Hepatitis E virus is an enterically transmitted virus that causes both epidemics and sporadic cases of acute hepatitis in many countries of Asia and Africa but only rarely causes disease in more industrialised countries.
A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species
TLDR
DNase treatment of serum samples may prove to be a very useful tool for virus discovery and the DNase-SISPA method is suitable for screening of a large number of samples and also enables rapid sequence determination of high-titer viruses.
Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries
TLDR
There was a difference in anti- HEV prevalence in both swine veterinarians and blood donors among the eight selected states, with subjects from Minnesota six times more likely to be anti-HEV positive than those from Alabama, and age was not a factor in the observed differences.
Hepatitis E: an emerging awareness of an old disease.
Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses
TLDR
HAV proteins are less homologous with those of any other picornavirus than the latter proteins are when compared with each other, and when the sequences of wild-type and cell culture-adapted HAV strains are compared, the nucleotide Differences in the 5' noncoding region and the amino acid differences in the capsid region suggest areas that may contain markers for cell culture adaptation and for attenuation.
The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies.
TLDR
Sequences within the HCV E1 and E2 envelope genes were analyzed during the acute phase of hepatitis C in 12 patients with different clinical outcomes to indicate that the evolutionary dynamics of theHCV quasispecies during the emergency phase predict whether the infection will resolve or become chronic.
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee.
TLDR
A stable infectious molecular clone of strain H77 (genotype 1a) of hepatitis C virus (HCV) is constructed and injection of RNA transcripts from this consensus clone into the liver of a chimpanzee resulted in viral replication.
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