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Deoxyribonucleases

Known as: Deoxyribonuclease, DNase, Deoxyribonucleases [Chemical/Ingredient] 
Enzymes that catalyze the hydrolytic cleavage of phosphodiester bond linkages in the DNA backbone. Deoxyribonucleases belong to a larger family of… Expand
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (23)

Acid DNaseAlkaline DNaseCAN2 protein, ArabidopsisDFFB protein, human
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Deoxyribonuclease Ab:ACnc:Pt:Ser:QnEnzyme GeneEsterase GeneHydrolase
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Broader (1)

phosphoric diester hydrolase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Predictions of Genetic Disease Many genome-wide association studies (GWAS) have identified loci and variants associated with… Expand
Highly Cited
2004
Highly Cited
2004
Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis.
BACKGROUND & AIMS We tested whether the attenuation of experimental colitis by live probiotic bacteria is due to their… Expand
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Highly Cited
1998
Highly Cited
1998
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
The homeostasis of animals is regulated not only by the growth and differentiation of cells, but also by cell death through a… Expand
Highly Cited
1990
Highly Cited
1990
The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene
We have isolated a cDNA clone, PU.1, that codes for a new tissue-specific DNA binding protein. Analysis of the binding site by… Expand
Highly Cited
1987
Highly Cited
1987
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
The enhancer-binding protein AP-1 has been purified to greater than 95% homogeneity from HeLa cells by sequence-specific DNA… Expand
Highly Cited
1983
Highly Cited
1983
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
Fractionation of HeLa cell extracts reveals the presence of a promoter-specific transcription factor, Sp 1, which activates a… Expand
Highly Cited
1978
Highly Cited
1978
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity.
A method for studying the sequence-specific binding of proteins to DBA is described. The technique is a simple conjoining of the… Expand
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Highly Cited
1977
Highly Cited
1977
Stable incorporation of plasmid DNA into higher plant cells: the molecular basis of crown gall tumorigenesis
Abstract Evidence is presented that crown gall tumors are caused by the incorporation of part of a virulence plasmid carried by… Expand
Highly Cited
1973
Highly Cited
1973
Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonuclease.
Abstract Evidence is presented that indicates a regular sub-structure in nuclear nucleoprotein with regularly distributed sites… Expand
Highly Cited
1961
Highly Cited
1961
The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides
A stable cell-free system has been obtained from E. coli which incorporates C14-valine into protein at a rapid rate. It was shown… Expand
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