Deoxyribonucleases

Known as: Deoxyribonuclease, DNase, Deoxyribonucleases [Chemical/Ingredient] 
Enzymes that catalyze the hydrolytic cleavage of phosphodiester bond linkages in the DNA backbone. Deoxyribonucleases belong to a larger family of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1943-2018
05010015019432017

Papers overview

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Highly Cited
2014
Highly Cited
2014
To the Editor: The majority of the gene variants discovered by nextgeneration sequencing (NGS) projects are either intronic or… (More)
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Highly Cited
2011
Highly Cited
2011
Sequence-specific nucleases represent valuable tools for precision genome engineering. Traditionally, zinc-finger nucleases (ZFNs… (More)
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Highly Cited
2011
Highly Cited
2011
The human body contains thousands of unique cell types, each with specialized functions. Cell identity is governed in large part… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS We tested whether the attenuation of experimental colitis by live probiotic bacteria is due to their… (More)
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Highly Cited
2000
Highly Cited
2000
Many bacterial pathogens encode a multisubunit toxin, termed cytolethal distending toxin (CDT), that induces cell cycle arrest… (More)
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Highly Cited
1998
Highly Cited
1998
The homeostasis of animals is regulated not only by the growth and differentiation of cells, but also by cell death through a… (More)
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Highly Cited
1990
Highly Cited
1990
We have isolated a cDNA clone, PU.1, that codes for a new tissue-specific DNA binding protein. Analysis of the binding site by… (More)
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Highly Cited
1987
Highly Cited
1987
We have constructed a "minilocus" that contains the 5' and 3' flanking regions of the human beta-globin locus and the beta-globin… (More)
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Highly Cited
1987
Highly Cited
1987
The enhancer-binding protein AP-1 has been purified to greater than 95% homogeneity from HeLa cells by sequence-specific DNA… (More)
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Highly Cited
1978
Highly Cited
1978
A method for studying the sequence-specific binding of proteins to DBA is described. The technique is a simple conjoining of the… (More)
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