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Daclizumab

Known as: Daclizumab beta, monoclonal antibody humanized anti-Tac, MOAB anti-Tac 
A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2… 
National Institutes of Health

Related topics

Related topics

13 relations
1 ML Daclizumab 150 MG/ML Prefilled Syringe [Zinbryta]Drug AllergyGraft-vs-Host DiseaseIGHG1 protein, human

Broader (4)

Antibodies, Monoclonal, HumanizedImmunoglobulin GImmunosuppressive AgentsMonoclonal Antibodies

Narrower (2)

Zinbrytayttrium Y 90 daclizumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Medical Management of Rheumatoid Arthritis
SIR,-The second report of the Royal College of Physicians-Smoking and Health Now'-once more gives clear evidence of the… 
Highly Cited
2004
Highly Cited
2004
Expression of the CXCR3 ligand I‐TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation
The factors that regulate lymphocyte traffic in chronic hepatitis C (CHC) are not completely defined. Interferon (IFN)‐inducible… 
Highly Cited
1989
Highly Cited
1989
Nature of the bifunctional chelating agent used for radioimmunotherapy with yttrium-90 monoclonal antibodies: critical factors in determining in vivo survival and organ toxicity.
One factor that is critical to the potential effectiveness of radioimmunotherapy is the design of radiometal-chelated antibodies… 
Highly Cited
1989
Highly Cited
1989
Promotion of human T lymphocyte proliferation by IL-4.
The capacity of human rIL-4 to support the proliferation of mitogen-stimulated T cells directly as well as by increasing IL-2… 
Highly Cited
1987
Highly Cited
1987
Interleukin 2 receptors are expressed by alveolar macrophages during pulmonary sarcoidosis and are inducible by lymphokine treatment of normal human lung macrophages, blood monocytes, and monocyte…
Expression of receptors for IL 2 was believed initially to be restricted to T cells after their activation by IL 1 and antigen… 
Highly Cited
1986
Highly Cited
1986
Mechanisms of age-related decline in antigen-specific T cell proliferative response: IL-2 receptor expression and recombinant IL-2 induced proliferative response of purified tac-positive T cells
Highly Cited
1985
Highly Cited
1985
A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.
Murine splenocytes immune to influenza virus-activated human T-cells were fused with SP2/0 cells, selected in chemically defined… 
Highly Cited
1985
Highly Cited
1985
Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes.
The antigen receptor molecules on human T lymphocytes are noncovalently associated on the cell surface with the CD3 (T3… 
Highly Cited
1985
Highly Cited
1985
Regulation of c-myc mRNA levels in normal human lymphocytes by modulators of cell proliferation.
Increased expression of the cellular oncogene c-myc has recently been demonstrated in some types of proliferating non-neoplastic… 
Highly Cited
1984
Highly Cited
1984
Stimulation of immunoglobulin secretion in human B lymphocytes as a direct effect of high concentrations of IL 2.
In certain human IgM and IgG cell lines, immunoglobulin (Ig) secretion is highly stimulated by a B cell inducing factor (BIF… 
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