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Daclizumab

Known as: Daclizumab beta, monoclonal antibody humanized anti-Tac, MOAB anti-Tac 
A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Some patients with severe asthma have frequent exacerbations associated with persistent eosinophilic inflammation… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The anti-human epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody trastuzumab improves the… Expand
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Highly Cited
2011
Highly Cited
2011
PURPOSE Trastuzumab is a humanized monoclonal antibody against the human epidermal growth factor receptor 2 (HER2). The clinical… Expand
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Highly Cited
2010
Highly Cited
2010
In an attempt to treat cancer patients with ERBB2 overexpressing tumors, we developed a chimeric antigen receptor (CAR) based on… Expand
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Review
2009
Review
2009
CD4(+) regulatory T cells frustrate productive tumor immune surveillance and represent an obstacle for cancer immunotherapy. In… Expand
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Highly Cited
2006
Highly Cited
2006
Administration of daclizumab, a humanized mAb directed against the IL-2Ralpha chain, strongly reduces brain inflammation in… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND A recombinant humanized anti-IgE mAb, omalizumab, forms complexes with free IgE, blocking its interaction with mast… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that… Expand
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Highly Cited
1998
Highly Cited
1998
Background Monoclonal antibodies that block the high-affinity interleukin-2 receptor expressed on alloantigen-reactive T… Expand
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Highly Cited
1996
Highly Cited
1996
PURPOSE Breast cancer frequently overexpresses the product of the HER2 proto-oncogene, a 185-kd growth factor receptor (p185HER2… Expand
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