Daclizumab

Known as: Daclizumab beta, monoclonal antibody humanized anti-Tac, MOAB anti-Tac 
A recombinant monoclonal antibody interleukin-2 receptor antagonist. Daclizumab binds specifically to the alpha subunit of the human interleukin-2… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
05019812017

Papers overview

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Review
2014
Review
2014
Cytoreductive surgery and chemotherapy continue to be the mainstay of ovarian cancer treatment. However, as mortality from… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Immunosuppressive regimens with the fewest possible toxic effects are desirable for transplant recipients. This study… (More)
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Highly Cited
2006
Highly Cited
2006
Administration of daclizumab, a humanized mAb directed against the IL-2Ralpha chain, strongly reduces brain inflammation in… (More)
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Highly Cited
2004
Highly Cited
2004
Identifying effective treatment combinations for MS patients failing standard therapy is an important goal. We report the results… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Acute rejection is still a major problem in renal transplantation and is one of the most important causes of chronic… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Monoclonal antibodies that block the high-affinity interleukin-2 receptor expressed on alloantigen-reactive T… (More)
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Highly Cited
1989
Highly Cited
1989
The anti-Tac monoclonal antibody is known to bind to the p55 chain of the human interleukin 2 receptor and to inhibit… (More)
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Highly Cited
1984
Highly Cited
1984
Interleukin 2 promotes proliferation of T cells by virtue of its interaction with a high-affinity cell surface receptor. This… (More)
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