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DNMT1 gene

Known as: DNA METHYLTRANSFERASE, DNMT1, DNA (Cytosine-5)-Methyltransferase 1 Gene 
This gene is involved in epigenetic modification of DNA.
National Institutes of Health

Related topics

Related topics

5 relations
DNA (cytosine-5-)-methyltransferase 1DNA MethylationDNA Modification MethylasesMethylation

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DNMT1 wt Allele

Papers overview

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Highly Cited
2014
Highly Cited
2014
MicroRNA-148b and microRNA-152 reactivate tumor suppressor genes through suppression of DNA methyltransferase-1 gene in pancreatic cancer cell lines
Overexpression of DNA methyltransferase 1 (DNMT-1) is observed mostly in pancreatic cancer and it can cause tumor suppressor… 
2014
2014
Effects of benzene and its metabolites on global DNA methylation in human normal hepatic l02 cells
Benzene is an important industrial chemical that is also widely present in cigarette smoke, automobile exhaust, and gasoline. It… 
Highly Cited
2013
Highly Cited
2013
MicroRNA‐140 acts as a liver tumor suppressor by controlling NF‐κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression
MicroRNAs (miRNAs) are small RNAs that regulate the expression of specific target genes. While deregulated miRNA expression… 
Highly Cited
2013
Highly Cited
2013
MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism.
Nickel (Ni) compounds are well-recognized human carcinogens, yet the molecular mechanisms by which they cause human cancer are… 
2011
2011
Expression and function role of DNA methyltransferase 1 in human bladder cancer
The identification of potential tumor markers will help improve therapeutic planning and patient management. Therefore, the aim… 
Highly Cited
2010
Highly Cited
2010
Domain-Specific Response of Imprinted Genes to Reduced DNMT1
ABSTRACT Imprinted genes are expressed in a monoallelic, parent-of-origin-specific manner. Clusters of imprinted genes are… 
2007
2007
Expression of human DNA methyltransferase 1 in colorectal cancer tissues and their corresponding distant normal tissues
Background and aimDNA methylation plays an important role during colorectal cancer (CRC) carcinogenesis. DNA methyltransferase 1… 
Review
2006
Review
2006
Reelin down-regulation in mice and psychosis endophenotypes
Highly Cited
2004
Highly Cited
2004
DNA Methyltransferase 1 Knock Down Induces Gene Expression by a Mechanism Independent of DNA Methylation and Histone Deacetylation*
DNA methyltransferase 1 (DNMT1) catalyzes the post-replication methylation of DNA and is responsible for maintaining the DNA… 
Highly Cited
2002
Highly Cited
2002
DNA Methyltransferase Deficiency Modifies Cancer Susceptibility in Mice Lacking DNA Mismatch Repair
ABSTRACT We have introduced DNA methyltransferase 1 (Dnmt1) mutations into a mouse strain deficient for the Mlh1 protein to study… 
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