FAQ

DNA Modification Methylases

Known as: DNA Methyltransferase, Modification Methylases, DNA, Modification Methylases 
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2017
05010019742017

Related topics

Related topics

17 relations
5,6-dihydro-5-azacytidineAzacitidineDNMT1 geneEnzyme Gene
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Narrower (2)

DNA methyltransferase M.BstC8I, Bacillus stearothermophilusDNA modification methylase XorII, Xanthomonas oryzae

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
DNA Modification Methylases
physiological aspects
In Blood
chemical synthesis
Azacitidine
decitabine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Epigenetic therapy in gastrointestinal cancer: the right combination.
Epigenetics is a relatively recent field of molecular biology that has arisen over the past 25 years. Cancer is now understood to… (More)
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Highly Cited
2011
Highly Cited
2011
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
The human genome is replete with long non-coding RNAs (lncRNA), many of which are transcribed and likely to have a functional… (More)
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Highly Cited
2008
Highly Cited
2008
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
Dicer initiates RNA interference by generating small RNAs involved in various silencing pathways. Dicer participates in… (More)
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Highly Cited
2008
Highly Cited
2008
DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity.
A clear understanding is developing concerning the importance of epigenetic-related molecular mechanisms in transcription… (More)
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Highly Cited
2007
Highly Cited
2007
Covalent Modification of DNA Regulates Memory Formation
DNA methylation is a covalent chemical modification of DNA catalyzed by DNA methyltransferases (DNMTs). DNA methylation is… (More)
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Highly Cited
2006
Highly Cited
2006
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
Here, we describe a role for mammalian DNA methyltransferases (DNMTs) in telomere length control. Mouse embryonic stem (ES) cells… (More)
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Highly Cited
2006
Highly Cited
2006
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.
DNA (cytosine-5) methylation represents one of the most widely used mechanisms of enduring cellular memory. Stable patterns of… (More)
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Highly Cited
2003
Highly Cited
2003
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Hypermethylation of CpG islands in the promoter regions is an important mechanism to silence the expression of many important… (More)
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Highly Cited
2003
Highly Cited
2003
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
Transcriptional silencing by CpG island methylation is a prevalent mechanism of tumor-suppressor gene suppression in cancers… (More)
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Highly Cited
2000
Highly Cited
2000
DNA methyltransferase Dnmt1 associates with histone deacetylase activity.
The DNA methyltransferase Dnmt1 is responsible for cytosine methylation in mammals and has a role in gene silencing. DNA… (More)
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