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DDR1 gene

Known as: EDDR1, Discoidin Domain Receptor Family, Member 1 Gene, RECEPTOR TYROSINE KINASE 6 
This gene plays a role in extracellular matrix communication processes.
National Institutes of Health

Related topics

Related topics

11 relations
Cell AdhesionDDR1 protein, humanDDR1 wt AlleleDiscoidin Domain Receptor 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Ionizing-radiation induced DNA double-strand breaks: a direct and indirect lighting up.
Highly Cited
2012
Highly Cited
2012
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
Nat. Cell Biol. 14, 355–365 (2012); published online 18 March 2012; corrected after print 18 April 2012 In the version of this… 
Highly Cited
2012
Highly Cited
2012
DDR complex facilitates global association of RNA Polymerase V to promoters and evolutionarily young transposons
The plant-specific DNA-dependent RNA polymerase V (Pol V) evolved from Pol II to function in an RNA-directed DNA methylation… 
Highly Cited
2010
Highly Cited
2010
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Regulatory ubiquitylation is emerging as an important mechanism to protect genome integrity in cells exposed to DNA damage… 
Highly Cited
2010
Highly Cited
2010
A Protein Complex Required for Polymerase V Transcripts and RNA- Directed DNA Methylation in Arabidopsis
Highly Cited
2009
Highly Cited
2009
Ataxia telangiectasia mutated activation by transcription‐ and topoisomerase I‐induced DNA double‐strand breaks
Ataxia telangiectasia mutated (ATM), the deficiency of which causes a severe neurodegenerative disease, is a crucial mediator for… 
Highly Cited
2008
Highly Cited
2008
Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions
The cellular DNA damage response (DDR) is initiated by the rapid recruitment of repair factors to the site of DNA damage to form… 
Highly Cited
2007
Highly Cited
2007
Dysfunctional telomeres activate an ATM‐ATR‐dependent DNA damage response to suppress tumorigenesis
The POT1 (protection of telomeres) protein binds the single‐stranded G‐rich overhang and is essential for both telomere end… 
Highly Cited
2002
Highly Cited
2002
Combined Functional Genomic Maps of the C. elegans DNA Damage Response
Many human cancers originate from defects in the DNA damage response (DDR). Although much is known about this process, it is… 
Highly Cited
1994
Highly Cited
1994
Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)
The activity of cyclin-dependent kinases (cdks) depends on the phosphorylation of a residue corresponding to threonine 161 in… 
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