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DDR1 protein, human

Known as: Epithelial Discoidin Domain-Containing Receptor 1, Protein-Tyrosine Kinase 3A, HGK2 
Epithelial discoidin domain-containing receptor 1 (913 aa, ~101 kDa) is encoded by the human DDR1 gene. This protein plays a role in tyrosine… 
National Institutes of Health

Related topics

Related topics

36 relations
BrainBreast CarcinomaCell AdhesionCell Differentiation process

Broader (3)

Discoidin Domain Receptor 1Receptor Protein-Tyrosine Kinasesdiscoidin receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase.
Dendritic patterning and spine morphogenesis are crucial for the assembly of neuronal circuitry to ensure normal brain… 
Review
2007
Review
2007
Regulation of chondrocyte differentiation by the actin cytoskeleton and adhesive interactions
Chondrocyte differentiation is a multi‐step process characterized by successive changes in cell morphology and gene expression… 
Highly Cited
2006
Highly Cited
2006
A Transmembrane Leucine Zipper Is Required for Activation of the Dimeric Receptor Tyrosine Kinase DDR1*
Receptor tyrosine kinases of the discoidin domain family, DDR1 and DDR2, are activated by different types of collagen and play… 
Highly Cited
2003
Highly Cited
2003
Molecular Analysis of Collagen Binding by the Human Discoidin Domain Receptors, DDR1 and DDR2
The widely expressed mammalian discoidin domain receptors (DDRs), DDR1 and DDR2, are unique among receptor tyrosine kinases in… 
Highly Cited
2002
Highly Cited
2002
Molecular cytogenetic analysis of head and neck squamous cell carcinoma: By comparative genomic hybridization, spectral karyotyping, and expression array analysis
A combination of molecular cytogenetic and expression array analysis has been performed on head and neck squamous cell carcinoma… 
Highly Cited
2000
Highly Cited
2000
Discoidin Domain Receptor 1 Is Activated Independently of β1 Integrin*
Various types of collagen have been identified as potential ligands for the two mammalian discoidin domain receptor (DDR… 
Highly Cited
1997
Highly Cited
1997
Overexpression of protein tyrosine kinases in human esophageal cancer.
Using a PCR-based cloning technique, we isolated a series of protein tyrosine kinases (PTKs) expressed in a cell line of… 
Highly Cited
1997
Highly Cited
1997
Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells.
Recent evidence indicates that integrin ligation results in activation of focal adhesion kinase (pp125FAK), the prototype of a… 
Highly Cited
1997
Highly Cited
1997
Differential Signaling by the Focal Adhesion Kinase and Cell Adhesion Kinase β*
pp125FAK and CAKβ/Pyk2/CadTK/RAFTK are related protein-tyrosine kinases. It is therefore of interest whether CAKβ shares some of… 
Highly Cited
1995
Highly Cited
1995
Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily (*)
A second protein-tyrosine kinase (PTK) of the focal adhesion kinase (FAK) subfamily, cell adhesion kinase β (CAKβ), was… 
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