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Corticotropin-Releasing Hormone

Known as: Corticotropin Releasing Factor, ACTH-Releasing Factor, Corticotropin-Releasing Hormone-41 
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR… 
National Institutes of Health

Related topics

Related topics

33 relations
CRH geneCRH wt AlleleCorticotropinCorticotropin releasing hormone:MCnc:Pt:Ser/Plas:Qn

Broader (4)

HormonesHypothalamic HormonesNeuropeptidesPeptides

Narrower (8)

UCN3 protein, humanastressinastressin Bcortagine

Papers overview

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Highly Cited
1999
Highly Cited
1999
Non-peptide corticotropin-releasing hormone antagonists: syntheses and structure-activity relationships of 2-anilinopyrimidines and -triazines.
Screening of our chemical library using a rat corticotropin-releasing hormone (CRH) receptor assay led to the discovery that 2… 
1999
1999
Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines.
The synthesis and CRF receptor binding affinities of several new series of N-aryltriazolo- and -imidazopyrimidines and -pyridines… 
Highly Cited
1986
Highly Cited
1986
Involvement of protein kinase C in the regulation of adrenocorticotropin release from rat anterior pituitary cells.
The involvement of protein kinase C in normal corticotroph function was studied by analysis of the effects of the phorbol ester… 
Highly Cited
1986
Highly Cited
1986
Gonadotropin-releasing hormone (GnRH) rapidly stimulates the formation of inositol phosphates and diacyglycerol in rat granulosa cells: further evidence for the involvement of Ca2+ and protein kinase…
GnRH provokes a phospholipid response in rat granulosa cells that has been characterized by increased incorporation of… 
Highly Cited
1984
Highly Cited
1984
Pituitary receptors for corticotropin-releasing factor: no effect of vasopressin on binding or activation of adenylate cyclase.
In this study we have characterized binding sites for ovine corticotropin-releasing factor (oCRF) in the rat anterior pituitary… 
Highly Cited
1983
Highly Cited
1983
Structural homology of corticotropin-releasing factor, sauvagine, and urotensin I: circular dichroism and prediction studies.
Three recently isolated peptides, whose sequences have been determined--the corticotropin (adrenocorticotropic hormone)-releasing… 
Highly Cited
1982
Highly Cited
1982
Amunine (ovine CRF), urotensin I and sauvagine, three structurally-related peptides, produce selective dilation of the mesenteric circulation.
Three synthetic peptides, urotensin I, sauvagine and ovine CRF, have less than 50% sequence homology. In the dog, all three… 
Highly Cited
1982
Highly Cited
1982
Thyrotropin-releasing hormone (TRH) selectively and rapidly stimulates phosphatidylinositol turnover in GH pituitary cells: a possible second step of TRH action.
TRH was found to rapidly influence 32PO4 incorporation into phospholipids of PRL-secreting GH pituitary cells. Analogs of TRH… 
Highly Cited
1972
Highly Cited
1972
Serum inactivation of the immunological and biological activity of thyrotropin releasing hormone (TRH).
The effect of human serum on the immunological and biological activity of thyrotropin releasing hormone (TRH) has been studied… 
Highly Cited
1969
Highly Cited
1969
Evidence for a diurnal rhythm of corticotropin-releasing factor (CRF) in the hypothalamus.
Although diurnal rhythms in pituitary ACTH, blood ACTH and plasma corticosterone levels have been described, such changes in CRF…