Corticotropin-Releasing Hormone

Known as: Corticotropin Releasing Factor, ACTH-Releasing Factor, Corticotropin-Releasing Hormone-41 
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
020040019512017

Papers overview

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Review
2017
Review
2017
Neuroinflammatory response is primarily a protective mechanism in the brain. However, excessive and chronic inflammatory… (More)
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Review
2016
Review
2016
Converging lines of evidence suggest that the pathophysiology of pain is mediated to a substantial degree via allostatic… (More)
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Highly Cited
2008
Highly Cited
2008
CONTEXT Genetic inheritance and developmental life stress both contribute to major depressive disorder in adults. Child abuse and… (More)
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Highly Cited
2000
Highly Cited
2000
Corticotropin-releasing hormone (Crh) is a critical coordinator of the hypothalamic-pituitary-adrenal (HPA) axis. In response to… (More)
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Highly Cited
2000
Highly Cited
2000
Corticotropin-releasing hormone (Crh), a 41-residue polypeptide, activates two G-protein–coupled receptors, Crhr1 (refs 3–5) and… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE The authors sought to carefully test, by using a technique of continuous CSF sampling, the hypothesis that basal… (More)
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Highly Cited
1998
Highly Cited
1998
Corticotropin-releasing hormone (CRH) is a potent mediator of endocrine, autonomic, behavioural and immune responses to stress… (More)
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Highly Cited
1995
Highly Cited
1995
CORTICOTROPIN-RELEASING factor (CRF), a peptide first isolated from mammalian brain1, is critical in the regulation of the… (More)
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Highly Cited
1994
Highly Cited
1994
The hypothalamo-pituitary-adrenal (HPA) axis is known to be activated in depressed patients. Although direct evidence is lacking… (More)
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Highly Cited
1987
Highly Cited
1987
There is now evidence that the immune system, during times of infectious challenge, can stimulate the secretion of… (More)
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