S. Yen

Publications485
h-index104
Citations36,306
Highly Influential Citations602
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The premenstrual syndrome.
  • R. Reid, S. Yen
  • Medicine, Psychology
    Clinical obstetrics and gynecology
  • 1 September 1983
TLDR
The reversible "medical ovariectomy" attained with this agonist suggests that it may be an effective and rational treatment for this distressing syndrome in the short term.
Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.
TLDR
Repairing DHEA and DS to young adult levels in men and women of advancing age induced an increase in the bioavailability of IGF-I, as reflected by an increases in IGF- I and a decrease in IGFBP-1 levels.
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age‐advanced men and women
TLDR
The effect of a larger dose (100 mg) of DHEA for a longer duration (6 months) on circulating sex steroids, body composition (DEXA) and muscle strength (MedX) was assessed.
Nutritional and endocrine-metabolic aberrations in amenorrheic athletes.
  • G. Laughlin, S. Yen
  • Biology, Medicine
    The Journal of clinical endocrinology and…
  • 1 December 1996
TLDR
Although neuroendocrine-metabolic adaptations to the energy cost of exercise training were evident in both groups of athletes, AA displayed alterations distinct from their cycling counterparts, with evidence of a hypometabolic state.
Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle.
TLDR
The inhibin-activin-follistatin system in the corpus luteum appears to function in an autocrine fashion, with remarkable switches in subunit gene expressions.
Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: common and distinct features.
TLDR
The basic tenet of this investigation was that obesity is not a prerequisite in the development of polycystic ovary syndrome, as indicated by the fact that 50% of PCOS women are not obese, and that obesity contributes an additional component to IR in obese PCOS.
Hormonal dynamics at midcycle: a reevaluation.
TLDR
The data provide a relatively precise picture of the hormonal changes preceding the onset of the gonadotropin surge and the temporal relationship between the multiphasic P4 rise and pituitary-ovarian function.
Alterations in the hypothalamic-pituitary-ovarian and the hypothalamic-pituitary-adrenal axes in athletic women.
TLDR
The functional integrity of the hypothalamic-pituitary-ovarian and leptin-adrenal axes was assessed by determining pulsatile LH, ACTH, and cortisol secretion during the early follicular phase in athletic women with regular menstrual cycles, and the groups did not differ in any 24-h ACTH pulse pattern parameter or in cortisol pulse frequencies.
A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.
TLDR
The data suggest that the DHEAS concentration is independently and inversely related to death from any cause and death from cardiovascular disease in men over age 50.
Hypoleptinemia in women athletes: absence of a diurnal rhythm with amenorrhea.
  • G. Laughlin, S. Yen
  • Biology, Medicine
    The Journal of clinical endocrinology and…
  • 1997
TLDR
Findings are consistent with a link between the functionality of adipocytes, nutritional status, and integrity of the reproductive axis in humans.
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