Skip to search formSkip to main contentSkip to account menu

astressin B

Known as: cyclo(30-33)(Phe(12),Nle(21),CalphaMeLeu(27),Glu(30),Lys(33),Nle(-38),CalphaMeLeu(40))Ac-hCRF(9-1), cyclo(30-33)(phenylalanyl(12)-norleucyl(21)-Calpha-methylleucyl(2-7)-glutamyl(30)-lysyl(33)-norleucyl(38)-Calpha-methyleucyl(40))acetyl-hCRF(9-41) 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Corticotropin-Releasing HormonePeptide Fragments

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Corticotropin-releasing factor peptide antagonists: Design, characterization and potential clinical relevance
Highly Cited
2012
Highly Cited
2012
CRF Induces Intestinal Epithelial Barrier Injury via the Release of Mast Cell Proteases and TNF-α
Background and Aims Psychological stress is a predisposing factor in the onset and exacerbation of important gastrointestinal… 
Highly Cited
2008
Highly Cited
2008
Suppression of the MEK/ERK signaling pathway reverses depression-like behaviors of CRF2-deficient mice
The neuropeptide corticotropin-releasing factor (CRF) plays a critical role in the proper functioning of the stress response… 
Highly Cited
2008
Highly Cited
2008
Astressin B, a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey.
Administration of ghrelin, a key peptide in the regulation of energy homeostasis, has been shown to decrease LH pulse frequency… 
2004
2004
Corticotropin-Releasing Hormone Antagonists, Astressin B and Antalarmin: Differing Profiles of Activity in Rhesus Monkeys
The present study compares the activity of two chemically distinct corticotropin-releasing hormone (CRH) antagonists at the level… 
Highly Cited
2004
Highly Cited
2004
Cocaine- and amphetamine-regulated transcript activates the hypothalamic-pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism.
Cocaine- and amphetamine-regulated transcript (CART) is a highly expressed hypothalamic transcript that is concentrated in areas… 
Highly Cited
1999
Highly Cited
1999
Constrained corticotropin releasing factor antagonists (astressin analogues) with long duration of action in the rat.
In an earlier report we identified specific modifications and substitutions of corticotropin releasing factor (CRF) that led to… 
1998
1998
Peripheral corticotropin-releasing factor mediates the elevation of plasma IL-6 by immobilization stress in rats.
We previously reported the elevation of plasma interleukin (IL)-6 activity in response to immobilization stress in rats. To… 
1998
1998
Astressin analogues (corticotropin-releasing factor antagonists) with extended duration of action in the rat.
In earlier reports we identified specific point substitutions (DPhe12,Nle21,38), cyclization strategies [in particular… 
Highly Cited
1995
Highly Cited
1995
Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor.
Predictive methods, physicochemical measurements, and structure activity relationship studies suggest that corticotropin… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)