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Coformycin

Known as: Coformycin [Chemical/Ingredient], Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)- 
A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Adenosine has been proposed to promote sleep through A1 receptors (A1R's) and/or A2A receptors in the brain. We previously… Expand
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2007
2007
Transition state theory suggests that enzymatic rate acceleration (kcat/knon) is related to the stabilization of the transition… Expand
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Highly Cited
2000
Highly Cited
2000
We have used an enzyme-based, twin-barrelled sensor to measure adenosine release during hypoxia in the CA1 region of rat… Expand
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Highly Cited
1998
Highly Cited
1998
The antifungal activity of the nucleoside analog 3'-deoxyadenosine (cordycepin) was studied in a murine model of invasive… Expand
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Highly Cited
1997
Highly Cited
1997
The purine nucleoside adenosine (9-beta-D-ribofuranosyladenine) inhibits a number of lymphocyte functions in vitro, including the… Expand
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1981
1981
 
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1980
1980
1. The catabolism of purine nucleotides was investigated by both chemical and radiochemical methods in isolated rat hepatocytes… Expand
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1976
1976
High concentrations of adenosine are known to be toxic to fibroblasts and lymphocytes under conditions of in vitro culture (1,2… Expand
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Highly Cited
1976
Highly Cited
1976
Activity of adenosine deaminase (ADA), an enzyme known to be deficient in some patients with severe combined immunodeficiency… Expand
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1975
1975
The non-steady state nature of the inhibition of milk xanthine oxidase by allopurinol and alloxanthine was demonstrated, and the… Expand
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