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Coformycin

Known as: Coformycin [Chemical/Ingredient], Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)- 
A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

Antibiotics, AntineoplasticEnzyme InhibitorsImmunosuppressive Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

isocoformycin

Papers overview

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Highly Cited
1991
Highly Cited
1991
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
1991
1991
Catabolism of adenine nucleotides in suspension-cultured plant cells.
Highly Cited
1987
Highly Cited
1987
Hamster cells with increased rates of DNA amplification, a new phenotype
Highly Cited
1980
Highly Cited
1980
Purine catabolism in isolated rat hepatocytes. Influence of coformycin.
1. The catabolism of purine nucleotides was investigated by both chemical and radiochemical methods in isolated rat hepatocytes… 
Highly Cited
1977
Highly Cited
1977
Specificity of adenosine deaminase inhibitors.
Highly Cited
1976
Highly Cited
1976
Inhibition of maturation of human precursor lymphocytes by coformycin, and inhibitor of the enzyme adenosine deaminase
High concentrations of adenosine are known to be toxic to fibroblasts and lymphocytes under conditions of in vitro culture (1,2… 
Highly Cited
1976
Highly Cited
1976
Adenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.
The association of a human genetic deficiency of adenosine deaminase activity with combined immunodeficiency prompted a study of… 
Highly Cited
1975
Highly Cited
1975
Effects of adenosine deaminase on cyclic adenosine monophosphate accumulation, lipolysis, and glucose metabolism of fat cells.
Highly Cited
1975
Highly Cited
1975
Adenosine deaminase from human erythrocytes: purification and effects of adenosine analogs.
Highly Cited
1974
Highly Cited
1974
Structure of coformycin, an unusual nucleoside of microbial origin.
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