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Coformycin

Known as: Coformycin [Chemical/Ingredient], Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)- 
A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

Antibiotics, AntineoplasticEnzyme InhibitorsImmunosuppressive Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

isocoformycin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Dominant localization of adenosine deaminase in leptomeninges and involvement of the enzyme in sleep.
Highly Cited
1991
Highly Cited
1991
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
1991
1991
Catabolism of adenine nucleotides in suspension-cultured plant cells.
1991
1991
Structure-activity relationship of ligands of human plasma adenosine deaminase2.
1990
1990
Catalytic and regulatory site composition of yeast AMP deaminase by comparative binding and rate studies. Resolution of the cooperative mechanism.
1983
1983
Inhibition of lymphocyte function by 9-deazaadenosine.
Highly Cited
1977
Highly Cited
1977
Specificity of adenosine deaminase inhibitors.
1977
1977
Pathways of nucleotide metabolism in Schistosoma mansoni--VII. Inhibition of adenine and guanine nucleotide synthesis by purine analogs in intact worms.
Highly Cited
1976
Highly Cited
1976
Inhibition of maturation of human precursor lymphocytes by coformycin, and inhibitor of the enzyme adenosine deaminase
High concentrations of adenosine are known to be toxic to fibroblasts and lymphocytes under conditions of in vitro culture (1,2… 
1976
1976
Adenosine metabolism in cultured lymphoid cells.
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