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The kinetic parameters of enzymes are key to understanding the rate and specificity of most biological processes. Although… Expand Coenzyme A (CoA) is a ubiquitous essential cofactor that plays a central role in the metabolism of carboxylic acids, including… Expand The hydroxyl group in the 3-position of the phenylpropanoid compounds is introduced at the level of coumarate shikimate/quinate… Expand CONTEXT
Molecular profiling of prostate cancer has led to the identification of candidate biomarkers and regulatory genes… Expand The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or statins are potent inhibitors of cholesterol biosynthesis… Expand BackgroundProspective studies indicate that baseline levels of C-reactive protein (CRP), the prototypic marker of inflammation… Expand CONTEXT
Increasing evidence suggests that cholesterol plays a role in the pathophysiology of Alzheimer disease (AD). For instance… Expand BACKGROUND
Cholesterol-lowering therapy can improve cardiovascular morbidity and mortality in patients with atherosclerosis… Expand Utilization of carbohydrate and fatty acids is strongly influenced by rates of con sumption and production of high energy… Expand The oxidation of ethanol to acetate by cultures of Methunobacillus omelianskii was found by Barker to be dependent upon carbon… Expand