Skip to search formSkip to main contentSkip to account menu

Ligase

Known as: EC 6, Ligases, Synthetases 
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (33)

2,3-dihydroxybenzoate-AMP ligase, E coli4-methyleneglutamine synthetase5-Formyltetrahydrofolate cyclo-ligase6-methylsalicylic acid synthetase
Coenzyme ADNA LigasesEnzyme GeneGlutamate-Cysteine Ligase

Broader (1)

Enzymes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1980
Highly Cited
1980
Benzidine binding to nucleic acids mediated by the peroxidative activity of prostaglandin endoperoxide synthetase.
The cooxidative metabolism of the urinary bladder carcinogen benzidine was examined using renal inner medullary microsomes. The… 
Highly Cited
1977
Highly Cited
1977
Isolation and characterization of independently folding regions of the beta chain of Escherichia coli tryptophan synthetase.
It had been reported previously that the beta2 subunit of Escherichia coli tryptophan synthetase [L-serinehydrolyase (adding… 
Highly Cited
1976
Highly Cited
1976
One-step purification and properties of a two-peptide fatty acid synthetase from the uropygial gland of the goose.
Cell-free extracts from the uropygial gland of goose catalyzed the incorporation of malonyl-CoA into normal fatty acids and… 
Highly Cited
1976
Highly Cited
1976
Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis.
The binding of deoxynucleoside 5'-monophosphates and various folate derivatives to Lactobacillus casei thymidylate synthetase was… 
Highly Cited
1972
Highly Cited
1972
Glycogen synthetase-D phosphatase. I. Some new properties of the partially purified enzyme from rabbit skeletal muscle.
Abstract Purification of the phospho-protein phosphatase of skeletal muscle which promotes the conversion of the phospho- (D or b… 
Highly Cited
1971
Highly Cited
1971
Mechanism of prostaglandin biosynthesis. I. Characterization and assay of bovine prostaglandin synthetase.
Highly Cited
1969
Highly Cited
1969
Regulation and mechanism of phosphoribosylpyrophosphate synthetase. I. Purification and properties of the enzyme from Salmonella typhimurium.
Abstract A procedure is described for a 450-fold purification of 5-phosphoribosyl α-1-pyrophosphate (PRPP) synthetase from cells… 
Highly Cited
1966
Highly Cited
1966
Inducibility of tryptophan synthetase in Pseudomonas putida.
The pathway of tryptophan synthesis in various microorganisms1-4 is shown in Figure 1. Although this reaction sequence is… 
Highly Cited
1966
Highly Cited
1966
Use of a filter-paper disk assay in the measurement of lipid biosynthesis.
The precipitation by trichloroacetic acid (TCA) of radioactive lipids on disks of filter-paper, followed by extraction with TCA… 
Highly Cited
1960
Highly Cited
1960
The synthesis of enzymes concerned in bacteriochlorophyll formation in growing cultures of Rhodopseudomonas spheroides.
SUMMARY: The enzymes λ-aminolaevulic acid synthetase and λ-aminolaevulic acid dehydrase are concerned in the early stages of…