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Ligase

Known as: EC 6, Ligases, Synthetases 
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The cellular response to external stress signals and DNA damage depends on the activity of ubiquitin ligases (E3s), which… Expand
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Review
2018
Review
2018
Ubiquitin-like proteins (Ubl's) are conjugated to target proteins or lipids to regulate their activity, stability, subcellular… Expand
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Review
2018
Review
2018
Mitochondria produce energy in the form of ATP via oxidative phosphorylation. As defects in oxidative phosphorylation can… Expand
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Review
2017
Review
2017
Nonribosomal peptide synthetases (NRPSs) are large multienzyme machineries that assemble numerous peptides with large structural… Expand
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Review
2017
Review
2017
Cells of all organisms survey problems during translation elongation, which may happen as a consequence of mRNA aberrations… Expand
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Review
2017
Review
2017
Aminoacyl-tRNA synthetases (ARSs) are responsible for charging amino acids to cognate tRNA molecules, which is the essential… Expand
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Review
2017
Review
2017
The Notch signaling pathway relies on a proteolytic cascade to release its transcriptionally active intracellular domain, on… Expand
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Review
2017
Review
2017
The first clinical description of Parkinson's disease (PD) will embrace its two century anniversary in 2017. For the past 30… Expand
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Review
2017
Review
2017
ABSTRACT Ubiquitination serves as a degradation mechanism of proteins, but is involved in additional cellular processes such as… Expand
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Review
2016
Review
2016
Nonribosomal peptides are amongst the most widespread and structurally diverse secondary metabolites in nature with many… Expand
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