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Ligase

Known as: EC 6, Ligases, Synthetases 
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by… 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
E3 ligases confer specificity to ubiquitination by recognizing target substrates and mediating transfer of ubiquitin from an E2… 
Highly Cited
2007
Highly Cited
2007
Auxin is a pivotal plant hormone that controls many aspects of plant growth and development. Perceived by a small family of F-box… 
Highly Cited
2006
Review
2005
Review
2005
Cullin–RING complexes comprise the largest known class of ubiquitin ligases. Owing to the great diversity of their substrate… 
Highly Cited
2004
Highly Cited
2004
NF-κB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-1… 
Highly Cited
2001
Highly Cited
2001
Skeletal muscle adapts to decreases in activity and load by undergoing atrophy. To identify candidate molecular mediators of… 
Highly Cited
2000
Highly Cited
2000
Autosomal recessive juvenile parkinsonism (AR–JP), one of the most common familial forms of Parkinson disease, is characterized… 
Review
1995
Review
1995
  • J. Hayes, D. Pulford
  • Critical reviews in biochemistry and molecular…
  • 1995
  • Corpus ID: 6998003
The glutathione S-transferases (GST) represent a major group of detoxification enzymes. All eukaryotic species possess multiple… 
Highly Cited
1991
Highly Cited
1991
The probability that a residue in a protein is part of a coiled-coil structure was assessed by comparison of its flanking…