• Publications
  • Influence
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.
White adipocytes are unique in that they contain large unilocular lipid droplets that occupy most of the cytoplasm. To identify genes involved in the maintenance of mature adipocytes, we expressedExpand
  • 342
  • 28
  • PDF
CGI-58 Interacts with Perilipin and Is Localized to Lipid Droplets
Lipid droplets (LDs) are a class of ubiquitous cellular organelles that are involved in lipid storage and metabolism. Although the mechanisms of the biogenesis of LDs are still unclear, a set ofExpand
  • 238
  • 14
MLDP, a Novel PAT Family Protein Localized to Lipid Droplets and Enriched in the Heart, Is Regulated by Peroxisome Proliferator-activated Receptor α*
Cytosolic lipid droplets (LDs) are multifunctional organelles that exist in all types of eukaryotic cells and control lipid homeostasis. In mammalian cells LDs contain a class of proteins in theirExpand
  • 174
  • 12
Insertion of the 70-kDa Peroxisomal Membrane Protein into Peroxisomal Membranes in Vivo and in Vitro(*)
Biosynthesis and intracellular transport of 70-kDa peroxisomal membrane protein (PMP70) has been studied in rat hepatoma, H-4-II-E cells. Pulse-chase analysis showed that a newly synthesized S-PMP70Expand
  • 124
  • 10
Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear
Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) and hepatocyte nuclear factor-4 (HNF-4) are orphan members of the steroid/thyroid receptor superfamily and exhibit ubiquitous andExpand
  • 101
  • 9
  • PDF
A unified nomenclature for peroxisome biogenesis factors
Ben Distel,* Ralf Erdmann, ¢ Stephen J. Gould, ~ Gtinter Blobel,I Denis I. Crane, I James M. Cregg,** Gabriele Dodt,* Yukio Fujiki, *~ Joel M. Goodman, ~ Wilhelm W. Just, D Jan A.K.W. Kiel, 11Expand
  • 399
  • 8
  • PDF
Amino-terminal presequence of the precursor of peroxisomal 3-ketoacyl-CoA thiolase is a cleavable signal peptide for peroxisomal targeting.
To examine the function of the amino-terminal presequence of rat peroxisomal 3-ketoacyl-CoA thiolase precursor, fusion proteins of various amino-terminal regions of the precursor with non-peroxisomalExpand
  • 272
  • 7
Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation*♦
Background: Perilipin family proteins are important in determining the properties of lipid droplets (LDs). Results: Perilipin 5-deficient mice lack detectable LDs, exhibit enhanced fatty acidExpand
  • 146
  • 7
CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation Published, JLR Papers in Press, February 17, 2007.
A lipid droplet (LD)-associated protein, perilipin, is a critical regulator of lipolysis in adipocytes. We previously showed that Comparative Gene Identification-58 (CGI-58), a product of the causalExpand
  • 149
  • 7
The transactivating function of peroxisome proliferator‐activated receptor γ is negatively regulated by SUMO conjugation in the amino‐terminal domain
Peroxisome proliferator‐activated receptor (PPAR)‐γ2, a member of the nuclear hormone receptor superfamily, plays a key role in adipocyte differentiation. Its amino‐terminal region carries aExpand
  • 133
  • 7