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Cocaine

Known as: Cocaine [Chemical/Ingredient], C, Snow 
A tropane alkaloid with central nervous systems (CNS) stimulating and local anesthetic activity. Cocaine binds to the dopamine, serotonin, and… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (19)

2,3-dehydrococaine3-(4-fluorobenzoyloxy)tropane3-hydroxybenzoylecgonine3-iodo-4-azidococaine

Broader (5)

AlkaloidsAminesCentral Nervous System StimulantsDopamine Uptake Inhibitors
Benzoylecgonine:MCnt:Pt:Hair:QnBenzoylecgonine:PrThr:Pt:Hair:OrdBenzoylecgonine:PrThr:Pt:Urine:Ord:SAMHSA screenCocaine Dependence

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Drug harms in the UK: a multicriteria decision analysis
Highly Cited
2004
Highly Cited
2004
Reinstatement of cocaine-reinforced responding in the rat
Non-contingent “priming” drug injections and conditioned stimuli associated with drug injections led to reinstatement of… 
Highly Cited
2003
Highly Cited
2003
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse
Repeated cocaine treatment and withdrawal produces changes in brain function thought to be involved in relapse to drug use… 
Review
2002
Review
2002
Neurobiology of Relapse to Heroin and Cocaine Seeking: A Review
The objective of this article is to review data from studies that used a reinstatement model in rats to elucidate the neural… 
Highly Cited
2001
Highly Cited
2001
Cardiovascular complications of cocaine use.
The deaths of several celebrities in recent years in association with the nontherapeutic use of cocaine have focused widespread… 
Highly Cited
2001
Highly Cited
2001
Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
Cocaine blocks uptake by neuronal plasma membrane transporters for dopamine (DAT), serotonin (SERT), and norepinephrine (NET… 
Highly Cited
1998
Highly Cited
1998
Regulation of cocaine reward by CREB.
Cocaine regulates the transcription factor CREB (adenosine 3', 5'-monophosphate response element binding protein) in rat nucleus… 
Highly Cited
1996
Highly Cited
1996
Activation of memory circuits during cue-elicited cocaine craving.
Evidence accumulated over more than 45 years has indicated that environmental stimuli can induce craving for drugs of abuse in… 
Review
1991
Review
1991
The dopamine hypothesis of the reinforcing properties of cocaine
Highly Cited
1987
Highly Cited
1987
Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
Although cocaine binds to several sites in the brain, the biochemical receptor mechanism or mechanisms associated with its… 
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