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Cocaine

Known as: Cocaine [Chemical/Ingredient], C, Snow 
A tropane alkaloid with central nervous systems (CNS) stimulating and local anesthetic activity. Cocaine binds to the dopamine, serotonin, and… Expand
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (19)

2,3-dehydrococaine3-(4-fluorobenzoyloxy)tropane3-hydroxybenzoylecgonine3-iodo-4-azidococaine
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Broader (5)

AlkaloidsAminesCentral Nervous System StimulantsDopamine Uptake Inhibitors
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Benzoylecgonine:MCnt:Pt:Hair:QnBenzoylecgonine:PrThr:Pt:Hair:OrdBenzoylecgonine:PrThr:Pt:Urine:Ord:SAMHSA screenCocaine Dependence
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Papers overview

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Review
2018
Review
2018
CNO Evil? Considerations for the Use of DREADDs in Behavioral Neuroscience
This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication. NPG are providing this early… Expand
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Highly Cited
2008
Highly Cited
2008
High impulsivity predicts the switch to compulsive cocaine-taking.
Both impulsivity and novelty-seeking have been suggested to be behavioral markers of the propensity to take addictive drugs… Expand
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Highly Cited
2007
Highly Cited
2007
Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.
Stimulant addiction is often linked to excessive risk taking, sensation seeking, and impulsivity, but in ways that are poorly… Expand
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Highly Cited
2003
Highly Cited
2003
Subsecond dopamine release promotes cocaine seeking
The dopamine-containing projection from the ventral tegmental area of the midbrain to the nucleus accumbens is critically… Expand
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Highly Cited
2001
Highly Cited
2001
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.
The role of limbic-striato-pallidal circuitry in cocaine-induced reinstatement was evaluated. The transient inhibition of brain… Expand
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Highly Cited
2000
Highly Cited
2000
Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli.
OBJECTIVE Cocaine-related cues have been hypothesized to perpetuate drug abuse by inducing a craving response that prompts drug… Expand
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Highly Cited
1999
Highly Cited
1999
Limbic activation during cue-induced cocaine craving.
OBJECTIVE Since signals for cocaine induce limbic brain activation in animals and cocaine craving in humans, the objective of… Expand
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Highly Cited
1997
Highly Cited
1997
Acute Effects of Cocaine on Human Brain Activity and Emotion
We investigated brain circuitry mediating cocaine-induced euphoria and craving using functional MRI (fMRI). During double-blind… Expand
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Highly Cited
1996
Highly Cited
1996
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
Disruption of the mouse dopamine transporter gene results in spontaneous hyperlocomotion despite major adaptive changes, such as… Expand
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Highly Cited
1987
Highly Cited
1987
Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
Although cocaine binds to several sites in the brain, the biochemical receptor mechanism or mechanisms associated with its… Expand
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