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Clofibrate

Known as: ELPI, Clofibric Acid, Ethyl Ester, Clofibrato 
An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (15)

AL 294AtromidLipofactonMagnesium Clofibrate

Broader (4)

Anticholesteremic AgentsAntilipemic agentHypolipidemic Agentschlorophenoxyacetate
Clofibrate:Mass:Pt:Dose:QnCoronary Artery DiseaseDecreased Lipolysis [PE]Drug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Platelet function and platelet phospholipids in patients with hyperbetalipoproteinemia. Effect of nicotinic acid and clofibrate.
. Platelet factor-3 activity and availability, platelet phospholipids, their fatty acid and aldehyde composition and plasma… 
2009
2009
Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols.
RATIONALE S-Nitrosothiols (SNO) inhibit immune activation of the respiratory epithelium and airway SNO levels are decreased in… 
2001
2001
On the Influence of Metal Alkoxides on the Epoxide Ring-Opening and Condensation Reactions of 3-Glycidoxypropyltrimethoxysilane
The extent of the epoxide ring-opening, the formation of ethyl ether groups as one reaction product of the ring-opening and the… 
1986
1986
Correspondence analysis applied to steroid receptor binding.
The relative binding affinities of 48 steroids for four classes of hormone receptor (progestin, PR; androgen, AR; glucocorticoid… 
1984
1984
Trisodium nitrilotriacetate monohydrate: promoting effects on the development of renal tubular cell tumors in rats treated with N-ethyl-N-hydroxyethylnitrosamine.
The effect of trisodium nitrilotriacetate monohydrate [N,N-bis(carboxymethyl)glycine trisodium salt] (Na3NTA X H2O) on… 
Highly Cited
1981
Highly Cited
1981
Induction of a novel long-chain acyl-CoA hydrolase in rat liver by administration of peroxisome proliferators.
The activity of long-chain acyl-CoA hydrolase in rat liver was increased by the administration of peroxisome proliferators, such… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
1975
1975
Cholestyramine, clofibrate and nicotinic acid as single or combined treatment of type IIa and IIb hyperlipoproteinaemia.
1. In type IIa and IIb hyperlipoproteinaemia, treatment with 16 g cholestyramine daily reduced the cholesterol concentration 23… 
Highly Cited
1971
Highly Cited
1971
Inhibition of hepatic triglyceride formation by clofibrate.
The effect of clofibrate (CPIB) on hepatic glycerolipid formation has been studied in vivo and in vitro in the rat. Feeding 0.25… 
Highly Cited
1964
Highly Cited
1964
HYPOLIPEMIA AND HEPATOMEGALY FROM ETHYL CHLOROPHENOXYISOBUTYRATE (CPIB) IN THE RAT.