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Clofibrate

Known as: ELPI, Clofibric Acid, Ethyl Ester, Clofibrato 
An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (15)

AL 294AtromidLipofactonMagnesium Clofibrate

Broader (4)

Anticholesteremic AgentsAntilipemic agentHypolipidemic Agentschlorophenoxyacetate
Clofibrate:Mass:Pt:Dose:QnCoronary Artery DiseaseDecreased Lipolysis [PE]Drug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Polycyclic aromatic hydrocarbon size distributions in aerosols from appliances of residential wood combustion as determined by direct thermal desorption—GC/MS
Highly Cited
2003
Highly Cited
2003
Ethyl Pyruvate Ameliorates Intestinal Epithelial Barrier Dysfunction in Endotoxemic Mice and Immunostimulated Caco-2 Enterocytic Monolayers
Ethyl pyruvate (EP) solution ameliorates ileal mucosal hyperpermeability and decreases the expression of several proinflammatory… 
Highly Cited
1984
Highly Cited
1984
Multiple forms of hepatic cytochrome P-450. Purification, characterisation and comparison of a novel clofibrate-induced isozyme with other major forms of cytochrome P-450.
In the present studies, a novel form of highly purified cytochrome P-450 (cytochrome P-452) isolated from the hepatic microsomes… 
Highly Cited
1983
Highly Cited
1983
Peroxisome proliferation in primary cultures of rat hepatocytes.
Highly Cited
1980
Highly Cited
1980
Acyl-CoA synthetase in rat liver peroxisomes. Computer-assisted analysis of cell fractionation experiments.
Highly Cited
1979
Highly Cited
1979
Effect of diosgenin on lipid metabolism in rats.
The purpose of this study was to determine whether diosgenin suppresses cholesterol absorption in rats, and to examine relevant… 
Highly Cited
1965
Highly Cited
1965
EFFECTS OF ALPHA-P-CHLOROPHENOXYISOBUTYRYL ETHYL ESTER (CPIB) WITH AND WITHOUT ANDROSTERONE ON CHOLESTEROL BIOSYNTHESIS IN RAT LIVER.
SUMMARY a-p-Chlorophenoxyisobutyrate (CPIB) or a mixture of CPIBwith a small amount of androsterone (Atromid) fed to rats at a… 
Highly Cited
1965
Highly Cited
1965
Papain Membrane on a Collodion Matrix: Preparation and Enzymic Behavior
A stable papain membrane has been prepared on a collodion matrix by absorbing papain in a collodion membrane and then cross… 
Highly Cited
1959
Highly Cited
1959
Biochemical Studies on the Toxicity of Tetraethyl Lead and Other Organo-Lead Compounds
The actions of purified tetra-, tri-, and di-ethyl lead on rats and rat brain slices and brain brei have been examined. A method… 
Highly Cited
1957
Highly Cited
1957
SOME PROPERTIES OF AN ESTERASE DERIVED FROM PREPARATIONS OF THE FIRST COMPONENT OF COMPLEMENT
Studies on an esterase derived from partially purified preparations of the first component of complement are described. The… 
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