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Clofibrate

Known as: ELPI, Clofibric Acid, Ethyl Ester, Clofibrato 
An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized… 
National Institutes of Health

Related topics

Related topics

37 relations

Narrower (15)

AL 294AtromidLipofactonMagnesium Clofibrate

Broader (4)

Anticholesteremic AgentsAntilipemic agentHypolipidemic Agentschlorophenoxyacetate
Clofibrate:Mass:Pt:Dose:QnCoronary Artery DiseaseDecreased Lipolysis [PE]Drug Allergy

Papers overview

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Highly Cited
2009
Highly Cited
2009
Platelet function and platelet phospholipids in patients with hyperbetalipoproteinemia. Effect of nicotinic acid and clofibrate.
. Platelet factor-3 activity and availability, platelet phospholipids, their fatty acid and aldehyde composition and plasma… 
2009
2009
A new anti-inflammatory derivative of imidazole which is less ulcerogenic than indomethacin in rats.
The mechanism of the anti-inflammatory activity and ulcerogenicity of (2-dimethylamino-1(2)-methyl) ethyl ester of the 1-(2… 
2001
2001
On the Influence of Metal Alkoxides on the Epoxide Ring-Opening and Condensation Reactions of 3-Glycidoxypropyltrimethoxysilane
The extent of the epoxide ring-opening, the formation of ethyl ether groups as one reaction product of the ring-opening and the… 
1986
1986
Correspondence analysis applied to steroid receptor binding.
The relative binding affinities of 48 steroids for four classes of hormone receptor (progestin, PR; androgen, AR; glucocorticoid… 
1986
1986
Modification of DNA and metabolism of ethyl carbamate in vivo: formation of 7-(2-oxoethyl)guanine and its sensitive determination by reductive tritiation using 3H-sodium borohydride.
The modification of liver DNA of mice and rats by ethyl carbamate and its putative proximate metabolite, vinyl carbamate, has… 
1977
1977
Autoradiographic and histopathologic studies on the mode of action of an aromatic retinoid (Ro 10-9359) on chemically induced epithelial tumors in Swiss mice.
The mode of action of an aromatic analogue of retinoic acid, ethyl all-trans-9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-2… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
1975
1975
Cholestyramine, clofibrate and nicotinic acid as single or combined treatment of type IIa and IIb hyperlipoproteinaemia.
1. In type IIa and IIb hyperlipoproteinaemia, treatment with 16 g cholestyramine daily reduced the cholesterol concentration 23… 
1966
1966
Rapid demonstration of juxtaglomerular granules in mammals and birds.
Slices of kidney, 3 mm thick, are fixed in 10% formalin containing 5% K2Cr2O7 and 2.5% acetic acid (Smith's fixative) for 18 hr… 
1933
1933
ACETYL-β‐METHYLCHOLIN I. THE ACTION ON NORMAL PERSONS. WITH A NOTE ON THE ACTION OF THE ETHYL ETHER OF β‐METHYLCHOLIN