Skip to search formSkip to main contentSkip to account menu

Cilazapril

Known as: 6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, 9-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)octahydro-10-oxo-, monohydrate, (1S-(1alpha,9alpha(R*)))-, CILAZAPRIL MONOHYDRATE, Cilazapril Hydrate 
A pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, cilazapril is rapidly metabolized in the… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive Agents
Cilazapril / HydrochlorothiazideIn Bloodagonistsanalogs & derivatives

Narrower (3)

InhibaceRo 31-2848cilazaprilat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Ultra-thin-layer chromatography mass spectrometry and thin-layer chromatography mass spectrometry of single peptides of angiotensin-converting enzyme inhibitors.
Highly Cited
1996
Highly Cited
1996
Antihypertensive drug treatment in chronic renal allograft rejection in the rat. Effect on structure and function.
To gain insight into the contribution of immunologic and hemodynamic factors in the progressive demise of structure and function… 
1996
1996
Effect of cilazapril on hyperdipsia in hemodialyzed patients.
To investigate whether angiotensin-converting enzyme inhibitor (ACE-I) potentially alleviates hyperdipsia, the effect of… 
1995
1995
Mechanism of inhibition of neointimal formation by the angiotensin-converting enzyme inhibitor cilazapril. A study in balloon catheter-injured rat carotid arteries.
We investigated the mechanism of inhibition of neointima formation by the angiotensin-covering enzyme the carotid artery. We… 
1993
1993
Effects of cilazapril on cerebral vasodilatation in hypertensive rats.
Endothelium-dependent dilatation of cerebral arterioles is impaired during chronic hypertension. The goal of this study was to… 
Highly Cited
1992
Highly Cited
1992
Quality of life with three antihypertensive treatments. Cilazapril, atenolol, nifedipine.
A multicenter, randomized double-blind study of 6 months' duration was performed in 540 patients (average age 54 years, 57% male… 
1991
1991
Heparin and Cilazapril Together Inhibit Injury‐Induced Intimal Hyperplasia
Both heparin and the angiotensin converting enzyme inhibitor cilazapril inhibit intimal thickening in rat carotid arteries… 
1988
1988
Antihypertensive effects and pharmacokinetics of single and consecutive doses of cilazapril in hypertensive patients with normal and impaired renal function.
The antihypertensive effects and pharmacokinetic properties of cilazapril, a long-acting angiotensin-converting enzyme (ACE… 
Highly Cited
1987
Highly Cited
1987
Repeated Administration of the Converting Enzyme Inhibitor Cilazapril to Normal Volunteers
Summary: Cilazapril 1.25 and 5.0 mg p.o. q.d. was administered in double-blind fashion to two groups of six normal volunteers on… 
1986
1986
The pharmacodynamics and dose-response relationships of the angiotensin converting enzyme inhibitor, cilazapril, in essential hypertension.
In a double-blind, placebo controlled, crossover study 12 patients with essential hypertension received single doses of 5, 10 and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)