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cilazaprilat

Known as: cilazaprilat anhydrous 
The active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug… 
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
To elucidate the local effects of renin in the coronary circulation, we examined local angiotensin (Ang) I and II formation, as… 
Highly Cited
1995
Highly Cited
1995
BACKGROUND Angiotensin-converting enzyme (ACE) produces angiotensin II, causing vasoconstriction of coronary arteries and… 
Highly Cited
1992
Highly Cited
1992
Studies were designed to investigate the mechanisms underlying the augmentation by angiotensin I converting enzyme (ACE… 
Highly Cited
1991
Highly Cited
1991
The effects of cilazaprilat were assessed on endothelium-dependent relaxations and contractions in isolated canine arteries. In… 
Highly Cited
1987
Highly Cited
1987
Summary: Cilazapril 1.25 and 5.0 mg p.o. q.d. was administered in double-blind fashion to two groups of six normal volunteers on… 
Highly Cited
1987
Highly Cited
1987
Summary: The pharmacokinetics of the new converting enzyme inhibitor cilazapril were investigated in 12 healthy male volunteers…