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cilazaprilat

Known as: cilazaprilat anhydrous 
The active metabolite of cilazapril, a pyridazine angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug… Expand
National Institutes of Health

Papers overview

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2002
2002
The present study was undertaken to clarify the role of intrarenal angiotensin (Ang) II and its generating pathways in clipped… Expand
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1999
1999
BACKGROUND Although ACE inhibitors can protect myocardium against ischemia/reperfusion injury, the mechanisms of this effect have… Expand
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1999
1999
The present study examined the role of intrarenal bradykinin in angiotensin-converting enzyme inhibitor (ACEI)-induced dilation… Expand
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Highly Cited
1998
Highly Cited
1998
To elucidate the local effects of renin in the coronary circulation, we examined local angiotensin (Ang) I and II formation, as… Expand
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1998
1998
The mechanism for hepatic uptake of temocaprilat, an angiotensin-converting enzyme inhibitor that is predominantly excreted into… Expand
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1995
1995
BACKGROUND Angiotensin-converting enzyme (ACE) produces angiotensin II, causing vasoconstriction of coronary arteries and… Expand
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Highly Cited
1992
Highly Cited
1992
Studies were designed to investigate the mechanisms underlying the augmentation by angiotensin I converting enzyme (ACE… Expand
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1991
1991
The effects of cilazaprilat were assessed on endothelium-dependent relaxations and contractions in isolated canine arteries. In… Expand
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Highly Cited
1987
Highly Cited
1987
Cilazapril 1.25 and 5.0 mg p.o. q.d. was administered in double-blind fashion to two groups of six normal volunteers on 8… Expand
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1987
1987
The pharmacokinetics of the new converting enzyme inhibitor cilazapril were investigated in 12 healthy male volunteers. Single… Expand
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