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Angiotensin-Converting Enzyme Inhibitors

Known as: Angiotensin Converting Enzyme Antagonists, Angiotensin I-Converting Enzyme Inhibitors, Inhibitors, Angiotensin-Converting Enzyme 
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting… 
National Institutes of Health

Related topics

Related topics

46 relations
Angiotensin II Type 1 Receptor BlockersAngiotensin-Converting Enzyme Inhibitors [MoA]Antihypertensive AgentsIn Blood

Narrower (37)

Benazepril hydrochloride 20 MG Oral TabletCaptoprilCaptopril / HydrochlorothiazideCilazapril

Broader (1)

Protease Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Role of Angiotensin in Pressure Overload‐Induced Hypertrophy in Rats: Effects of Angiotensin‐Converting Enzyme Inhibitors, an AT1 Receptor Antagonist, and Surgical Reversal
Summary The renin-angiotensin system (RAS) has been proposed to play a major role in causing the heart to hypertrophy during… 
Highly Cited
1985
Highly Cited
1985
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Structure 3a, a potent angiotensin-converting enzyme inhibitor, was prepared in five steps from L-(+)-alpha-amino-4-phenylbutyric… 
1985
1985
A radioimmunoassay for the angiotensin converting enzyme inhibitor ramipril and its active metabolite.
A radioimmunoassay (RIA) has been developed for the measurement of 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S… 
Highly Cited
1982
Highly Cited
1982
The Effects of Captopril on Rat Aortic Angiotensin‐Converting Enzyme
Summary Angiotensin-converting enzyme (ACE) activity was found to be present within the rat aorta using radioenzymatic techniques… 
Highly Cited
1980
Highly Cited
1980
Effect of acute lung injury on angiotensin converting enzyme in serum, lung lavage, and effusate.
The administration of an acute pulmonary edemagenic dose (ip) of thiourea to rats results in an elevation of angiotensin… 
1980
1980
Effect of paraquat on serum angiotensin converting enzyme.
Intraperitoneal administration of paraquat to mice produced a linear dose-response increase (20 to 50 mg/kg of body weight) in… 
Highly Cited
1979
Highly Cited
1979
Hemodialysis-resistant hypertension: control with an orally active inhibitor of angiotensin-converting enzyme.
In two patients with end stage renal disease and dialysis-resistant hypertension, the orally active inhibitor of angiotensin… 
Highly Cited
1979
Highly Cited
1979
Effect of atropine and vagotomy on response of transplanted pancreas.
It is well established that atropine and vagotomy inhibit pancreatic enzyme secretion in response to intestinal stimulants such… 
Highly Cited
1978
Highly Cited
1978
Distribution and development of angiotensin converting enzyme in the fetal and newborn rabbit. An immunofluorescence study.
The distribution and development of angiotensin converting enzyme (EC 3.4.15.1) were studied in fetal and newborn rabbits, using… 
Highly Cited
1976
Highly Cited
1976
Response to angiotensins I and II and to AI-converting-enzyme inhibitor in a shark.
The spiny dogfish shark, which does not have renal juxtaglomerular cells, exhibits a strong pressor response to both angiotensin…