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Angiotensin-Converting Enzyme Inhibitors
Known as:
Angiotensin Converting Enzyme Antagonists
, Angiotensin I-Converting Enzyme Inhibitors
, Inhibitors, Angiotensin-Converting Enzyme
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A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting…
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National Institutes of Health
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Related topics
Related topics
46 relations
Angiotensin II Type 1 Receptor Blockers
Angiotensin-Converting Enzyme Inhibitors [MoA]
Antihypertensive Agents
In Blood
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Narrower (37)
Benazepril hydrochloride 20 MG Oral Tablet
Captopril
Captopril / Hydrochlorothiazide
Cilazapril
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Broader (1)
Protease Inhibitors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1995
Review
1995
Angiotensin converting enzyme inhibitors, left ventricular hypertrophy and fibrosis
W. Linz
,
G. Wiemer
,
+5 authors
B. Schölkens
Molecular and Cellular Biochemistry
1995
Corpus ID: 3239888
From pharmacological investigations and clinical studies, it is known that angiotensin converting enzyme (ACE) inhibitors exhibit…
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Highly Cited
1986
Highly Cited
1986
Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations.
E. Thorsett
,
E. Harris
,
+7 authors
E. Ulm
Journal of Medicinal Chemistry
1986
Corpus ID: 41828761
A series of inhibitors of angiotensin converting enzyme (ACE, dipeptidyl carboxypeptidase, EC 3.4.15.1) is described which…
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Highly Cited
1985
Highly Cited
1985
Conformational analysis and active site modelling of angiotensin-converting enzyme inhibitors.
P. Andrews
,
J. Carson
,
A. Caselli
,
M. Spark
,
R. Woods
Journal of Medicinal Chemistry
1985
Corpus ID: 36480280
The discovery of captopril as a potent, orally active inhibitor of angiotensin-converting enzyme (ACE) led to the recent…
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Highly Cited
1982
Highly Cited
1982
The Effects of Captopril on Rat Aortic Angiotensin‐Converting Enzyme
P. Velletri
,
B. L. Bean
Journal of Cardiovascular Pharmacology
1982
Corpus ID: 19280135
Summary Angiotensin-converting enzyme (ACE) activity was found to be present within the rat aorta using radioenzymatic techniques…
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Highly Cited
1980
Highly Cited
1980
Effect of acute lung injury on angiotensin converting enzyme in serum, lung lavage, and effusate.
M. Hollinger
,
S. Giri
,
S. Patwell
,
J. Zuckerman
,
A. Gorin
,
G. Parsons
American Review of Respiratory Disease
1980
Corpus ID: 26733681
The administration of an acute pulmonary edemagenic dose (ip) of thiourea to rats results in an elevation of angiotensin…
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1980
1980
Effect of paraquat on serum angiotensin converting enzyme.
M. Hollinger
,
S. Patwell
,
J. Zuckerman
,
A. Gorin
,
G. Parsons
,
S. Giri
American Review of Respiratory Disease
1980
Corpus ID: 37190393
Intraperitoneal administration of paraquat to mice produced a linear dose-response increase (20 to 50 mg/kg of body weight) in…
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Highly Cited
1979
Highly Cited
1979
Converting Enzyme Inhibition with an Orally Active Compound in Hypertensive Man
E. Bravo
,
R. Tarazi
HYPERTENSION
1979
Corpus ID: 6016660
SUMMARY The short-terra cardiovascular and endocrine effects of an orally active anglotensin converting enzyme inhibitor, SQ14…
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Highly Cited
1979
Highly Cited
1979
Hemodialysis-resistant hypertension: control with an orally active inhibitor of angiotensin-converting enzyme.
E. Vaughan
,
R. Carey
,
C. Ayers
,
M. Peach
Journal of Clinical Endocrinology and Metabolism
1979
Corpus ID: 32141634
In two patients with end stage renal disease and dialysis-resistant hypertension, the orally active inhibitor of angiotensin…
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Highly Cited
1976
Highly Cited
1976
Response to angiotensins I and II and to AI-converting-enzyme inhibitor in a shark.
D. Opdyke
,
R. Holcombe
American Journal of Physiology
1976
Corpus ID: 30193267
The spiny dogfish shark, which does not have renal juxtaglomerular cells, exhibits a strong pressor response to both angiotensin…
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Highly Cited
1973
Highly Cited
1973
Intraluminal and postabsorptive effects of amino acids on pancreatic enzyme secretion
DiMagno Ep
,
Go Vl
,
Summerskill Hj
1973
Corpus ID: 88619328
Abstract Cholecystokinin-pancreozymin (CCK-PZ) was measured by a bioassay method based on pancreatic enzyme output in response to…
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