FAQ

Angiotensin-Converting Enzyme Inhibitors

Known as: Angiotensin Converting Enzyme Antagonists, Angiotensin I-Converting Enzyme Inhibitors, Inhibitors, Angiotensin-Converting Enzyme 
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting… (More)

Topic mentions per year

Topic mentions per year

1974-2017
050019742017

Related topics

Related topics

47 relations
Angiotensin II Type 1 Receptor BlockersAngiotensin-Converting Enzyme Inhibitors [MoA]Antihypertensive AgentsIn Blood
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Narrower (32)

CaptoprilCaptopril / HydrochlorothiazideCilazaprilEnalapril
(More)

Broader (1)

Protease Inhibitors

Related mentions per year

Related mentions per year

1943-2018
19401960198020002020
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Renin-angiotensin system
Protease Inhibitors
Captopril
Enalapril

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Angiotensin-converting-enzyme inhibition in stable coronary artery disease.
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors are effective in reducing the risk of heart failure, myocardial… (More)
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Highly Cited
2003
Highly Cited
2003
A comparison of outcomes with angiotensin-converting--enzyme inhibitors and diuretics for hypertension in the elderly.
BACKGROUND Treatment of hypertension with diuretics, beta-blockers, or both leads to improved outcomes. It has been postulated… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial.
BACKGROUND Angiotensin II type 1 receptor blockers have favourable effects on haemodynamic measurements, neurohumoral activity… (More)
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Highly Cited
2003
Highly Cited
2003
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial.
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors improve outcome of patients with chronic heart failure (CHF). A… (More)
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Highly Cited
2001
Highly Cited
2001
Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data.
PURPOSE To examine the efficacy of ACE inhibitors for treatment of nondiabetic renal disease. DATA SOURCES 11 randomized… (More)
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Highly Cited
2000
Highly Cited
2000
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.
A novel human zinc metalloprotease that has considerable homology to human angiotensin-converting enzyme (ACE) (40% identity and… (More)
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1999
1999
Design of angiotensin converting enzyme inhibitors
Specific inhibitors of angiotensin-converting enzyme, known to the lay public as ACE inhibitors, have now been embraced by the… (More)
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Highly Cited
1998
Highly Cited
1998
Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?
BACKGROUND Previous studies have reported an increased risk of cancer with calcium-channel blockers in man. Other work in animals… (More)
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Highly Cited
1997
Highly Cited
1997
Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans.
BACKGROUND The angiotensin-converting enzyme (ACE) not only generates angiotensin II but is also the main enzyme that destroys… (More)
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Highly Cited
1995
Highly Cited
1995
A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study…
BACKGROUND Treatment with angiotensin-converting-enzyme (ACE) inhibitors reduces mortality among survivors of acute myocardial… (More)
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