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Captopril

Known as: CPT, Captoprilum, (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline 
A sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (5)

Amino Acids, CyclicAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsEnzyme Inhibitors
AngioedemaAngiotensin-Converting Enzyme Inhibitors [MoA]AngiotensinsBartter Disease

Narrower (16)

ApoprilCapotenCaptolaneCaptopril / Hydrochlorothiazide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
The use of CPT for calculating axial capacity of drilled shafts
Highly Cited
1989
Highly Cited
1989
Evaluation of hypertensive patients by means of captopril enhanced renal scintigraphy with technetium-99m DTPA.
One-hundred five hypertensive patients underwent conventional renal scintigraphy followed 2 or 3 days later by Captopril-enhanced… 
1986
1986
Low‐Dose Captopril in Mild to Moderate Geriatric Hypertension
The safety and efficacy of Captopril in geriatric patients with mild to moderate hypertension was examined in an eight‐week… 
Highly Cited
1984
Highly Cited
1984
effects of Captopril on Limiting Infarct Size in Conscious Dogs
Summary: The effects of angiotensin-converting enzyme inhibitor captopril on infarct size and cardiovascular hemodynamics were… 
1983
1983
Long-term antihypertensive therapy with captopril.
Most forms of hypertension require life-long treatment; thus, it is important to determine the continuing effectiveness and… 
Highly Cited
1982
Highly Cited
1982
The Effects of Captopril on Rat Aortic Angiotensin‐Converting Enzyme
Summary Angiotensin-converting enzyme (ACE) activity was found to be present within the rat aorta using radioenzymatic techniques… 
Highly Cited
1981
Highly Cited
1981
Captopril combined with thiazide lowers renin substrate concentration: implications for methodology in renin assays.
1. We have measured plasma concentrations of renin, renin substrate and angiotensins I and II as well as plasma renin activity in… 
Highly Cited
1981
Highly Cited
1981
Blood Concentration and Urinary Excretion of Captopril (SQ 14,225) in Patients with Chronic Renal Failure
SUMMARY Blood concentration and urinary excretion of captopril following SO mg oral administration were determined by high… 
Highly Cited
1980
Highly Cited
1980
Hemodynamic and Volume Changes Associated with Captopril
SUMMARY The effects of captopril on bemodynamic, rolmne, and neurohumoral indices were inrestigated in 33 patients with essential… 
Highly Cited
1980
Highly Cited
1980
The Antihypertensive Effect of Captopril
SUMMARY The acute effect of the orally-active converting enzyme inhibitor, captopril, was compared to that of saralasin in 13…