Captopril

Known as: CPT, Captoprilum, (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline 
A sulfhydryl-containing analog of proline with antihypertensive activity and potential antineoplastic activity. Captopril competitively inhibits… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors such as captopril reduce mortality and cardiovascular morbidity among… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND ACE inhibitors attenuate the detrimental effects of angiotensin II, and improve survival and reduce morbidity in… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The ELITE study showed an association between the angiotensin II antagonist losartan and an unexpected survival… (More)
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Highly Cited
2000
Highly Cited
2000
A novel human zinc metalloprotease that has considerable homology to human angiotensin-converting enzyme (ACE) (40% identity and… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Angiotensin-converting-enzyme (ACE) inhibitors have been used for more than a decade to treat high blood pressure… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To determine whether tight control of blood pressure with either a beta blocker or an angiotensin converting enzyme… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND To determine whether specific angiotensin II receptor blockade with losartan offers safety and efficacy advantages in… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Left ventricular dilatation and dysfunction after myocardial infarction are major predictors of death. In experimental… (More)
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Highly Cited
1985
Highly Cited
1985
To determine whether the relationship between infarct size and ventricular performance, volume, and compliance could be altered… (More)
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Highly Cited
1985
Highly Cited
1985
Although vasodilator therapy has been shown to improve functional capacity in patients with congestive heart failure, there is no… (More)
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