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- Publications
- Influence
Plasminogen activator inhibitors.
- E. Sprengers, C. Kluft
- Medicine
- Blood
- 1987
Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen… Expand
The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection.
- G. Willemsen, J. Vink, +19 authors D. Boomsma
- Medicine
- Twin research and human genetics : the official…
- 1 February 2013
Over the past 25 years, the Adult Netherlands Twin Register (ANTR) has collected a wealth of information on physical and mental health, lifestyle, and personality in adolescents and adults. This… Expand
Consumption of black and green tea has no effect on inflammation, haemostasis and endothelial markers in smoking healthy individuals
- M. Maat, H. Pijl, C. Kluft, H. Princen
- Medicine
- European Journal of Clinical Nutrition
- 1 October 2000
Obejective: Firstly, to study the effect of tea and tea polyphenols on cardiovascular risk indicators of the inflammatory system (IL6, IL1β and TNF-α, CRP), and on haemostasis and endothelial… Expand
CD4 T lymphocytes from patients with chronic fatigue syndrome have decreased interferon-gamma production and increased sensitivity to dexamethasone.
- J. Visser, B. Blauw, +4 authors L. Nagelkerken
- Medicine
- The Journal of infectious diseases
- 1 February 1998
A disturbed hypothalamus-pituitary-adrenal gland axis and alterations at the immune system level have been observed in patients with chronic fatigue syndrome (CFS). Glucocorticoids are known to… Expand
Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in postmenopausal women with NIDDM
- H. Brussaard, J. Leuven, M. Frölich, C. Kluft, H. Krans
- Biology, Medicine
- Diabetologia
- 1997
Summary Oestrogen replacement therapy is associated with a decreased risk of cardiovascular disease in postmenopausal women. Patients with non-insulin-dependent diabetes mellitus (NIDDM) have an… Expand
Major circadian fluctuations in fibrinolytic factors and possible relevance to time of onset of myocardial infarction, sudden cardiac death and stroke.
- F. Andreotti, G. Davies, +5 authors C. Kluft
- Medicine
- The American journal of cardiology
- 15 September 1988
Natural inhibitors of endogenous fibrinolysis may displace the hemostatic equilibrium toward thrombosis and favor events such as acute myocardial infarction, sudden cardiac death and stroke, where a… Expand
Both raloxifene and estrogen reduce major cardiovascular risk factors in healthy postmenopausal women: A 2-year, placebo-controlled study.
- G. W. de Valk-de Roo, C. Stehouwer, +6 authors C. Netelenbos
- Medicine
- Arteriosclerosis, thrombosis, and vascular…
- 1 December 1999
Currently raloxifene, a selective estrogen receptor modulator, is being investigated as a potential alternative for postmenopausal hormone replacement to prevent osteoporosis and cardiovascular… Expand
Daytime fluctuations in blood of tissue-type plasminogen activator (t-PA) and its fast-acting inhibitor (PAI-1).
- C. Kluft, A. Jie, D. Rijken, J. Verheijen
- Medicine
- Thrombosis and haemostasis
- 8 April 1988
Circadian fluctuation in blood fibrinolytic activity was studied in 10 volunteers in the day-time period at 09.00, 12.00 and 15.00 h. Activity of tissue-type plasminogen activator (t-PA) was found to… Expand
Effect of oral contraceptives on haemostasis variables.
- C. Kluft, M. Lansink
- Medicine
- Thrombosis and haemostasis
- 1 July 1997
Combined oral contraceptives (COCs) have effects on a large number of haemostasis variables. We have summarised literature data on effects of COCs containing 30-35 micrograms ethinyl estradiol for… Expand
Progress of fibrinolysis during tumor necrosis factor infusions in humans. Concomitant increase in tissue-type plasminogen activator, plasminogen activator inhibitor type-1, and fibrin(ogen)…
- V. V. van Hinsbergh, K. Bauer, +4 authors W. Nieuwenhuizen
- Medicine
- Blood
- 1 December 1990
Several investigators have reported that tumor necrosis factor (TNF) can alter the production of plasminogen activator type-1 (PAI-1) and plasminogen activators (PAs) by endothelial cells in vitro.… Expand