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Chemokine (C-C Motif) Receptor 5

Known as: CKR5 Receptors, Receptors, CCR5, Antigens, CD195 
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B… 
National Institutes of Health

Related topics

Related topics

8 relations
CCR5 geneIn Bloodagonistsaspects of radiation effects

Narrower (2)

CCR5 protein, humanCCR5 receptor (222-240)

Broader (1)

Receptors, Cytokine

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cardiovascular , Pulmonary and Renal Pathology CCR 5 Signaling Suppresses Inflammation and Reduces Adverse Remodeling of the Infarcted Heart , Mediating Recruitment of Regulatory T Cells
Myocardial infarction triggers an inflammatory reaction that is involved in cardiac remodeling. Cardiac repair is dependent on… 
Highly Cited
2008
Highly Cited
2008
Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection.
BACKGROUND We conducted subanalyses of the combined results of the Maraviroc versus Optimized Therapy in Viremic Antiretroviral… 
Highly Cited
2005
Highly Cited
2005
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion
Human immunodeficiency virus type 1 (HIV-1) continues to spread, principally by heterosexual sex, but no vaccine is available… 
Highly Cited
2003
Highly Cited
2003
Use of a Small Molecule CCR5 Inhibitor in Macaques to Treat Simian Immunodeficiency Virus Infection or Prevent Simian–Human Immunodeficiency Virus Infection
Human immunodeficiency virus type 1 (HIV-1) fuses with cells after sequential interactions between its envelope glycoproteins… 
Highly Cited
2002
Highly Cited
2002
Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation.
Chemokines regulate the trafficking of leukocytes in immunity and inflammation and have been implicated in mouse models in acute… 
Highly Cited
2001
Highly Cited
2001
CC chemokine receptor 5 and renal-transplant survival
Highly Cited
2000
Highly Cited
2000
Maturation and Trafficking of Monocyte-Derived Dendritic Cells in Monkeys: Implications for Dendritic Cell-Based Vaccines1
Human dendritic cells (DC) have polarized responses to chemokines as a function of maturation state, but the effect of maturation… 
Highly Cited
1998
Highly Cited
1998
Natural Infection of a Homozygous Δ24 CCR5 Red-capped Mangabey with an R2b-Tropic Simian Immunodeficiency Virus
A homozygous 24-bp deletion (Δ24) was found in the CC chemokine receptor 5 (CCR5) of 11 out of 15 red-capped mangabeys (RCMs… 
Review
1997
Review
1997
Host factors in the pathogenesis of HIV disease
Host factors play an important role in determining rates of disease progression in human immunodeficiency virus (HIV)‐infected… 
Highly Cited
1996
Highly Cited
1996
Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors
HIV-1 actively replicates in dendritic cell (DC)-T cell cocultures, but it has been difficult to demonstrate substantial… 
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