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To update the American College of Rheumatology (ACR) 2000 recommendations for hip and knee osteoarthritis (OA) and develop new… Expand Tissue injury generates endogenous factors that heighten our sense of pain by increasing the response of sensory nerve endings to… Expand The capsaicin (vanilloid) receptor VR1 is a cation channel expressed by primary sensory neurons of the "pain" pathway… Expand Capsaicin, a pungent ingredient of hot peppers, causes excitation of small sensory neurons, and thereby produces severe pain. A… Expand Natural products afford a window of opportunity to study important biology. If the natural product is used or abused by human… Expand Pain-producing heat is detected by several classes of nociceptive sensory neuron that differ in their thermal response thresholds… Expand Capsaicin, the main pungent ingredient in "hot" chili peppers, elicits buming pain by activating specific (vanilloid) receptors… Expand Capsaicin, the main pungent ingredient in ‘hot’ chilli peppers, elicits a sensation of burning pain by selectively activating… Expand 1 Capsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin. The present study shows the capsazepine acts… Expand Etude du mecanisme d'action des neurones sensoriels et des fonctions de leurs effecteurs locaux en reponse a differents stimuli… Expand