Cannabinoid Receptor Agonists

Central nervous system responses to cannabis are primarily mediated by CB(1) receptors, which couple preferentially to G(i/o) G… (More)

Recent studies suggest that the endocannabinoid system modulates feeding. Despite the existence of central mechanisms for the… (More)

Cannabinoids exert pleiotropic actions in the CNS, including the inhibition of inflammatory responses and the enhancement of… (More)

1. We have studied the effect of cannabinoid agonists (CP 55,940 and cannabinol) on intestinal motility in a model of intestinal… (More)

BACKGROUND SR141716, a recently developed CB1 cannabinoid receptor antagonist, blocks acute effects of Delta-9… (More)

Two subtypes of the cannabinoid receptor (CB1 and CB2) are expressed in mammalian tissues. Although selective antagonists are… (More)

Tolerance develops rapidly to cannabis, cannabinoids, and related drugs acting at the CB1 cannabinoid receptor. However, little… (More)

The G-protein-coupled central cannabinoid receptor (CB1) has been shown to be functionally associated with several biological… (More)

Arachidonylethanolamide (anandamide), a candidate endogenous cannabinoid ligand, has recently been isolated from porcine brain… (More)

A cDNA clone encoding a receptor protein which presents all the characteristics of a guanine-nucleotide-binding protein (G… (More)