CRKL protein

Known as: CRK-Like Protein, CRKL, Crk-L adaptor 
Crk-like protein (303 aa, ~34 kDa) is encoded by the human CRKL gene. This protein is involved in both protein phosphorylation and signal… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
The Crk adaptor proteins (Crk and CrkL) constitute an integral part of a network of essential signal transduction pathways in… (More)
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Highly Cited
2006
Highly Cited
2006
Dasatinib (BMS-354825), a novel dual SRC/BCR-ABL kinase inhibitor, exhibits greater potency than imatinib mesylate (IM) and… (More)
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Highly Cited
2006
Highly Cited
2006
22q11 deletion (del22q11) syndrome is characterized genetically by heterozygous deletions within chromosome 22q11 and clinically… (More)
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Highly Cited
2001
Highly Cited
2001
Heterozygous deletions within human chromosome 22q11 are the genetic basis of DiGeorge/velocardiofacial syndrome (DGS/VCFS), the… (More)
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Highly Cited
2000
Highly Cited
2000
Hepatocyte growth factor (HGF; scatter factor) is a multipotent protein with mitogenic, motogenic, and developmental functions… (More)
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Review
2000
Review
2000
The Met receptor tyrosine kinase is the prototypic member of a small subfamily of growth factor receptors that when activated… (More)
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Highly Cited
1996
Highly Cited
1996
Chronic myelogenous leukemia (CML) and some acute lymphoblastic leukemias (ALL) are caused by the t(9;22) chromosome… (More)
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Highly Cited
1994
Highly Cited
1994
The Philadelphia chromosome (Ph1), detected in virtually all cases of chronic myelogenous leukemia (CML), is formed by a… (More)
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Highly Cited
1994
Highly Cited
1994
The chimeric BCR/ABL protein is characteristic of Philadelphia (Ph)+ leukemia because it is the direct product of the Ph… (More)
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Highly Cited
1994
Highly Cited
1994
Chronic myelogenous leukemia (CML) is characterized by the presence of the Philadelphia (Ph) chromosome in clonally derived… (More)
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