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Focal adhesion pathway

Known as: Focal Adhesion, Integrin-mediated Cell Adhesion, cell adhesion mediated by integrin 
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric… 
National Institutes of Health

Related topics

Related topics

50 relations
ACTB wt AlleleACTN1 protein, humanAKT1 wt AlleleARHGAP5 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Syndecan-4 and focal adhesion function.
Highly Cited
1998
Highly Cited
1998
The Urokinase-type Plasminogen Activator Receptor Mediates Tyrosine Phosphorylation of Focal Adhesion Proteins and Activation of Mitogen-activated Protein Kinase in Cultured Endothelial Cells*
Urokinase-type plasminogen activator (uPA) binds to cells via a specific glycosylphosphatidylinositol-anchored receptor. Although… 
Highly Cited
1997
Highly Cited
1997
Reversible Disruption of Cell-Matrix and Cell-Cell Interactions by Overexpression of Sialomucin Complex*
Sialomucin complex (SMC) is a large, heterodimeric glycoprotein complex composed of mucin (ASGP-1) and transmembrane (ASGP-2… 
Highly Cited
1996
Highly Cited
1996
Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation
Integrins alpha v beta 3 and alpha v beta 5 both mediate cell adhesion to vitronectin yet trigger different postligand binding… 
Highly Cited
1995
Highly Cited
1995
Tyrosine Phosphorylation of p130Cas and Cortactin Accompanies Integrin-mediated Cell Adhesion to Extracellular Matrix (*)
We show in this report that two v-src substrate proteins, p130 and cortactin, become tyrosine-phosphorylated during integrin… 
Highly Cited
1995
Highly Cited
1995
Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
The BCR/ABL oncogene causes chronic myelogenous leukemia (CML) in humans and induces growth factor independence of hematopoietic… 
Highly Cited
1995
Highly Cited
1995
SPARC mediates focal adhesion disassembly in endothelial cells through a follistatin‐like region and the Ca2+‐binding EF‐hand
SPARC is a one of a group of extracellular matrix proteins that regulate cell adhesion through a loss of focal adhesion plaques… 
Highly Cited
1993
Highly Cited
1993
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.
Treatment of Swiss 3T3 cells with bombesin caused a striking increase (21-fold) in the tyrosine phosphorylation of the… 
Highly Cited
1991
Highly Cited
1991
Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin [published erratum appears in J Cell Biol 1992 Feb;116(3):833]
Tenascin, together with thrombospondin and SPARC, form a family of matrix proteins that, when added to bovine aortic endothelial… 
Highly Cited
1986
Highly Cited
1986
Focal adhesion sites and the removal of substratum-bound fibronectin
Fibronectin was not removed from the substratum beneath focal adhesion sites when fibroblasts spread in serum-free medium on… 
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