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ACTN1 protein, human

Known as: actinin, alpha 1 protein, human, Non-Muscle Alpha-Actinin-1, Actinin 1 Smooth Muscle 
Alpha-actinin-1 (892 aa, ~103 kDa) is encoded by the human ACTN1 gene. This protein plays a role in F-actin crosslinking.
National Institutes of Health

Papers overview

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2009
2009
The acid-sensing ion channel 1a (ASIC1a) is widely expressed in central and peripheral neurons where it generates transient… Expand
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2008
2008
Actin stress fibers (SFs) enable cells to sense and respond to mechanical stimuli and affect adhesion, motility and apoptosis. We… Expand
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Highly Cited
2008
Highly Cited
2008
Actin assembly at the cell front drives membrane protrusion and initiates the cell migration cycle. Microtubules (MTs) extend… Expand
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2007
2007
Force generated in contractile actin filament bundles (stress fibers-SFs) is transmitted to the extracellular matrix (ECM) via… Expand
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Highly Cited
2006
Highly Cited
2006
While the role of titin as a sarcomeric protein is well established, its potential functional role(s) in smooth muscles and non… Expand
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2004
2004
PURPOSE To characterize properties of Pdlim2, a novel PDZ and LIM domain-containing protein. METHODS cDNA encoding Pdlim2 was… Expand
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Highly Cited
2003
Highly Cited
2003
Dominantly inherited mutations in ACTN4, which encodes alpha-actinin-4, cause a form of human focal and segmental… Expand
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2002
2002
To gain insight into the dynamic properties of focal contacts, we induced expression of green fluorescent protein-tagged beta3… Expand
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2000
2000
A 38-kd protein that associates with F-actin structures in activated platelets and endothelial cells was purified, cloned, and… Expand
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Highly Cited
1999
Highly Cited
1999
Subcellular targeting and the activity of facilitative glucose transporters are likely to be regulated by interactions with… Expand
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