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Erythropoietin Signaling Pathway

Known as: EPO Signaling Pathway 
Erythropoietin functions to increase the number of red blood cells. Thus, it has found utility as a drug for those needing to replenish erythrocytes… 
National Institutes of Health

Related topics

Related topics

48 relations
CRKL proteinCSNK2A1 wt AlleleELK1 wt AlleleEPO protein, human

Papers overview

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2005
2005
Glomerular Localization of Erythropoietin Receptor mRNA and Protein in Neonatal and Mature Mouse Kidney
Background/Aims: Erythropoietin (EPO) possesses well-established hematopoietic properties as the primary stimulator of red blood… 
Highly Cited
2000
Highly Cited
2000
The SH2 Inositol 5-Phosphatase Ship1 Is Recruited in an SH2-dependent Manner to the Erythropoietin Receptor*
Ship1 (SH2 inositol 5-phosphatase 1) has been shown to be a target of tyrosine phosphorylation downstream of cytokine and… 
1999
1999
Activation of the erythropoietin receptor is not required for internalization of bound erythropoietin.
Erythropoietin (EPO) is required for the survival and expansion of red blood cell progenitor cells and supports continued… 
1999
1999
HGF Activates Signal Transduction from EPO Receptor on Human Cord Blood CD34+/CD45+ Cells
Hepatocyte growth factor (HGF) is a multifunctional cytokine with early hematopoiesis‐stimulatory activity. Here, we focus on its… 
1998
1998
Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization
Highly Cited
1996
Highly Cited
1996
Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells.
The aim of the present study was to determine whether stem cell factor (SCF) and erythropoietin (EPO) act differently on defined… 
1993
1993
Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line
The Friend spleen focus-forming virus (SFFV) gp55 glycoprotein binds to the erythropoietin receptor (EPO-R), causing constitutive… 
1993
1993
Effect of tunicamycin treatment on ligand binding to the erythropoietin receptor: conversion from two classes of binding sites to a single class.
Scatchard analyses of erythropoietin (EPO) binding to its receptor (EPO-R) have shown that some erythroid cells display a… 
1992
1992
Activation of the erythropoietin receptor by the Friend spleen focus-forming virus gp55 glycoprotein induces constitutive protein tyrosine phosphorylation.
The erythropoietin receptor (EPO-R) can be activated to signal cell growth by binding either EPO or gp55, the Friend spleen focus… 
Review
1992
Review
1992
The interaction of the erythropoietin receptor and gp55.
Friend virus induced erythroleukaemia can be conveniently divided into a first stage and a second stage. The first stage results… 
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