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CES2 gene

Known as: CE-2, iCE, CES2A1 
This gene is involved in xenobiotic detoxification.
National Institutes of Health

Related topics

Related topics

5 relations
CES1 geneCES1P1 geneCES2 protein, humanHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A novel 15-spiro diterpenoid dimer from Andrographis paniculata with inhibitory potential against human carboxylesterase 2.
2019
2019
Identification and Characterization of a New Carboxylesterase 2 Isozyme, mfCES2C, in the Small Intestine of Cynomolgus Monkeys
In contrast to a single human carboxylesterase 2 (CES2) isozyme (hCE2), three CES2 genes have been identified in cynomolgus… 
2019
2019
Demethylbellidifolin isolated from Swertia bimaculate against human carboxylesterase 2: Kinetics and interaction mechanism merged with docking simulations.
2015
2015
Identification of tissue-restricted bioreaction suitable for in vivo targeting by fluorescent substrate library-based enzyme discovery.
Tissue-restricted bioreactions can be utilized to design chemical-biological tools and prodrugs. We have developed a fluorescent… 
2015
2015
Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes
Objective: The aim of this article is to elucidate the metabolic pathways of BJ-B11, a heat shock protein 90 inhibitor, in human… 
2013
2013
Efficacy of Low-Dose Oral Metronomic Dosing of the Prodrug of Gemcitabine, LY2334737, in Human Tumor Xenografts
LY2334737, an oral prodrug of gemcitabine, is cleaved in vivo, releasing gemcitabine and valproic acid. Oral dosing of mice… 
2011
2011
Abstract 2981: Carboxylesterase 2 hydrolyzes a gemcitabine prodrug (LY2334737) and provides a patient tailoring biomarker
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL LY2334737 (LY) is a prodrug analog of gemcitabine with… 
2003
2003
Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2).
Twelve novel single nucleotide polymorphisms (SNPs) were found in the CES2 gene from 153 Japanese individuals, who were… 
1997
1997
Caenorhabditis elegans has two isozymic forms, CE-1 and CE-2, of fructose-1,6-bisphosphate aldolase which are encoded by different genes.
Two distinct types of cDNAs for fructose-1,6-bisphosphate (FBP) aldolase, Ce-1 and Ce-2, have been isolated from nematode… 
1986
1986
ELECTROPHORETIC ANALYSIS OF LIVER NEURAMINIDASE‐1 VARIATION IN MICE AND ADDITIONAL EVIDENCE CONCERNING THE LOCATION OF NEU‐1
Neuraminidase‐1 (NEU‐1) is one of two neuraminidase isozymes which can be detected electrophoretically in mouse liver extracts… 
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