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CES2 gene

Known as: CE-2, iCE, CES2A1 
This gene is involved in xenobiotic detoxification.
National Institutes of Health

Papers overview

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2018
2018
BACKGROUND Carboxylesterases (CEs) belong to the serine hydrolase family, and are in charge of hydrolyzing chemicals with… Expand
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2017
2017
Summary Serine hydrolases are a large family of multifunctional enzymes known to influence obesity. Here, we performed activity… Expand
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Highly Cited
2015
Highly Cited
2015
A new ratiometric florescence probe derived from 3-hydroxyflavone (3-HF) has been developed for selective and sensitive detection… Expand
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2015
2015
Fructus Psoraleae (FP) is an edible Chinese herbal which is widely used in Asia for the treatment of various diseases including… Expand
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2011
2011
The purpose of this study was to develop an analytical method to quantify the relative activities of carboxylesterases (CESs) in… Expand
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2007
2007
PurposeCarboxylesterase 2 (CES2) is involved in the activation of the anticancer drug irinotecan to its active metabolite SN-38… Expand
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2007
2007
CPT-11 [7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin or Irinotecan] is a carbamate prodrug that is… Expand
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2004
2004
Carboxylesterases are members of the serine esterase super family important in the metabolism of a wide variety of substrates… Expand
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Highly Cited
2002
Highly Cited
2002
The prodrug irinotecan is an active agent for the treatment of advanced colorectal cancer and a number of other solid tumors… Expand
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1997
1997
Two distinct types of cDNAs for fructose-1,6-bisphosphate (FBP) aldolase, Ce-1 and Ce-2, have been isolated from nematode… Expand
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