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Bromodomain

A motif common in chromatin remodeling factors. It consists of approximately 110 amino acids in a left-handed up-and-down four helix bundle with a… 
National Institutes of Health

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Related topics

10 relations
BRD4 protein, humanBRDT protein, humanBromodomain Containing Protein 2Bromodomain-Containing Protein 3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Meeting the Challenge of Identifying New Treatments for Type 2-low Neutrophilic Asthma.
2015
2015
MicroRNA‐410 promotes cell proliferation by targeting BRD7 in non‐small cell lung cancer
2015
2015
The epigenetically active small chemical N-methyl pyrrolidone (NMP) prevents estrogen depletion induced osteoporosis.
2014
2014
Disrupting the Interaction of BRD 4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer
Jian Shi,1,4 Yifan Wang,1,4,5 Lei Zeng,6 Yadi Wu,2,4 Jiong Deng,7 Qiang Zhang,6 Yiwei Lin,1,4 Junlin Li,1,4 Tiebang Kang,5 Min… 
Highly Cited
2014
Highly Cited
2014
The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors
Endogenous c-MYC (MYC) has been reported to be a potential pharmacological target to trigger ubiquitous tumor regression of… 
Review
2014
Review
2014
BET bromodomain inhibitors—A novel epigenetic approach in castration-resistant prostate cancer
The androgen receptor (AR) is central to the initiation and progression of prostate cancer, even after castration. There has been… 
Highly Cited
2006
Highly Cited
2006
SWI/SNF Displaces SAGA-Acetylated Nucleosomes
ABSTRACT SWI/SNF is a well-characterized chromatin remodeling complex that remodels chromatin by sliding nucleosomes in cis and… 
Highly Cited
2005
Highly Cited
2005
Multiple Bromodomain Genes Are Involved in Restricting the Spread of Heterochromatic Silencing at the Saccharomyces cerevisiae HMR-tRNA Boundary
The transfer RNA gene downstream from the HMR locus in S. cerevisiae functions as part of a boundary (barrier) element that… 
Highly Cited
2001
Highly Cited
2001
Induction-independent Recruitment of CREB-binding Protein to the c-fos Serum Response Element through Interactions between the Bromodomain and Elk-1*
Proliferative signals lead to the rapid and transient induction of the c-fos proto-oncogene by targeting the ternary complex… 
Highly Cited
2000
Highly Cited
2000
Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9.
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