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BRDT protein, human

Known as: RING3-Like Protein, Cancer/Testis Antigen 9, Bromodomain Testis-Specific Protein 
Bromodomain testis-specific protein (947 aa, ~108 kDa) is encoded by the human BRDT gene. This protein plays a role in chromatin remodeling during… 
National Institutes of Health

Related topics

Related topics

8 relations
BRDT geneBromodomainGenes, RegulatorMeiosis

Broader (1)

Nuclear Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes†
Abstract JQ1 is a small-molecule inhibitor of the bromodomain and extra terminal (BET) protein family that potently inhibits the… 
Review
2020
Review
2020
BET proteins: Investigating BRDT as a potential target for male contraception.
2019
2019
Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
Upon intravenous injection of tumour necrosis factor (TNF) in mice, a systemic inflammatory response syndrome (SIRS) is initiated… 
2018
2018
BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis
The double bromodomain and extra-terminal domain (BET) proteins are critical epigenetic readers that bind to acetylated histones… 
2016
2016
Identification of novel potent human testis-specific and bromodomain-containing protein (BRDT) inhibitors using crystal structure-based virtual screening
Human testis-specific and bromodomain-containing protein (hBRDT) is essential for chromatin remodeling during spermatogenesis and… 
Review
2016
Review
2016
The control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon's head to tail
Male infertility due to abnormal spermatozoa has been reported in both animals and humans, but its pathogenic causes, including… 
2013
2013
Rituximab resistance in lymphoma Testis speci fi c gene expression drives disease progression and Rituximab resistance in lymphoma
Activation of cancer promoting genes or silencing of tumour suppressors is often due to aberrant expression of transcription… 
2013
2013
Testis specific gene expression drives disease progression and Rituximab resistance in lymphoma
Activation of cancer promoting genes or silencing of tumour suppressors is often due to aberrant expression of transcription… 
2012
2012
The role of Brdt, a double bromodomain testis-specific protein, in spermatogenesis: Chromatin organization and mRNA splicing
Review
2005
Review
2005
Bipolar Radiofrequency Dissection Tonsillectomy: A Prospective Randomized Trial
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