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Binding Sites

Known as: Site, Combining, Binding Site, Sites, Binding 
The parts of a macromolecule that directly participate in its specific combination with another molecule.
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

Binding Sites, AntibodyG-Protein-Coupled ReceptorsLigand Binding DomainSecond Messenger Systems
Protein BindingProtein Interaction MappingReceptors, Cell Surfaceaspects of radiation effects

Broader (1)

Proteins

Papers overview

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Highly Cited
2006
Highly Cited
2006
Global mapping of c-Myc binding sites and target gene networks in human B cells
The protooncogene MYC encodes the c-Myc transcription factor that regulates cell growth, cell proliferation, cell cycle, and… 
Highly Cited
1999
Highly Cited
1999
The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene*
The endogenous CYP2B6 gene becomes phenobarbital (PB) inducible in androstenol-treated HepG2 cells either transiently or stably… 
Highly Cited
1998
Highly Cited
1998
Cisplatin Binding Sites on Human Albumin*
Reactions of cisplatin (cis-[PtCl2(NH3)2]) with albumin are thought to play an important role in the metabolism of this… 
Highly Cited
1995
Highly Cited
1995
Distribution of GLP‐1 Binding Sites in the Rat Brain: Evidence that Exendin‐4 is a Ligand of Brain GLP‐1 Binding Sites
The distribution and biochemical properties of glucagon‐like peptide (GLP)‐1(7–36)amide (GLP‐1) binding sites in the rat brain… 
Highly Cited
1988
Highly Cited
1988
Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims.
Previous studies have provided evidence that corticotropin releasing factor (CRF) is hypersecreted in patients with major… 
Review
1988
Review
1988
A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules
Class II and class I histocompatibility molecules allow T cells to recognize 'processed' polypeptide antigens1–5. The two… 
Highly Cited
1988
Highly Cited
1988
Sugar and signal-transducer binding sites of the Escherichia coli galactose chemoreceptor protein.
D-galactose-binding (or chemoreceptor) protein of Escherichia coli serves as an initial component for both chemotaxis towards… 
Highly Cited
1987
Highly Cited
1987
High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine…
Scatchard analysis of binding of 125l‐basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the… 
Highly Cited
1981
Highly Cited
1981
Discrimination of Multiple [3H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain
Certain neuroleptic drugs, such as spiperone and (+) butaclamol, can discriminate between two populations of [3H]5… 
Highly Cited
1973
Highly Cited
1973
Insulin interactions with its receptors: experimental evidence for negative cooperativity.
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