G-Protein-Coupled Receptors

Known as: Receptors, G Protein Coupled, G Protein-Complex Receptors, coupled g protein receptors 
Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning… (More)
National Institutes of Health

Related topics

Related topics

50 relations
ADGRA2 geneG Protein-Coupled Receptor GenesG-protein coupled receptor activityGPR119 gene
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Narrower (33)

Aplnr protein, mouseAplnr protein, ratCCXCR1 receptor, humanEMR2 protein, human
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Broader (1)

Binding Sites

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Molecular signatures of G-protein-coupled receptors
G-protein-coupled receptors (GPCRs) are physiologically important membrane proteins that sense signalling molecules such as… (More)
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Review
2012
Review
2012
Restructuring G-Protein- Coupled Receptor Activation
G-protein-coupled receptors serve as key signal transduction conduits, linking extracellular inputs with diverse cellular… (More)
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Highly Cited
2010
Highly Cited
2010
Ligand-specific regulation of the extracellular surface of a G protein coupled receptor
G-protein-coupled receptors (GPCRs) are seven-transmembrane proteins that mediate most cellular responses to hormones and… (More)
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Review
2006
Review
2006
Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors.
G-protein-coupled receptors (GPCRs) participate in virtually all physiological processes. They constitute the largest and most… (More)
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Highly Cited
2006
Highly Cited
2006
Opsins and clusters of sensory G-protein-coupled receptors in the sea urchin genome.
Rhodopsin-type G-protein-coupled receptors (GPCRs) contribute the majority of sensory receptors in vertebrates. With 979 members… (More)
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Highly Cited
2005
Highly Cited
2005
Expression of G protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors.
In Escherichia coli and other cell-based expression systems, there are critical difficulties in synthesizing membrane proteins… (More)
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2002
2002
Bioinformatical analysis of G-protein-coupled receptors.
G-protein-coupled receptors play a key role in cellular signaling networks that regulate various physiological processes, such as… (More)
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Review
2001
Review
2001
Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Membrane proteins, encoded by ~20% of genes in almost all organisms, including humans, are critical for cellular communication… (More)
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Highly Cited
2000
Highly Cited
2000
Crystal structure of rhodopsin: A G protein-coupled receptor.
Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors (GPCRs) respond to a variety of different… (More)
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Review
1999
Review
1999
Regulation of tyrosine kinase cascades by G-protein-coupled receptors.
Mitogenic signaling by G-protein-coupled receptors (GPCRs) involves tyrosine phosphorylation of adaptor proteins and assembly of… (More)
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