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Ligand Binding Domain

Known as: Binding Site, Binding Site Domain, ligand-binding domain 
A Binding Site Domain is a region of protein that physically interacts stereospecifically, and usually at high affinity, with a specific ligand… 
National Institutes of Health

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Binding Sitesreceptor

Papers overview

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Highly Cited
1999
Highly Cited
1999
A Human Immunoglobulin (Ig)A Cα3 Domain Motif Directs Polymeric Ig Receptor–mediated Secretion
Polymeric immunoglobulins provide immunological protection at mucosal surfaces to which they are specifically transported by the… 
Highly Cited
1998
Highly Cited
1998
Interactions of Nickel(II) with histones: interactions of Nickel(II) with CH3CO-Thr-Glu-Ser-His-His-Lys-NH2, a peptide modeling the potential metal binding site in the "C-Tail" region of histone H2A.
A combined pH-metric and spectroscopic (UV/vis, CD, NMR) study of the Ni(II) binding to CH3CO-Thr-Glu-Ser-His-His-Lys-NH2… 
Highly Cited
1998
Highly Cited
1998
Structural studies of binding site tryptophan mutants in the high-affinity streptavidin-biotin complex.
Previous thermodynamic and computational studies have pointed to the important energetic role of aromatic contacts in generating… 
Highly Cited
1996
Highly Cited
1996
Structural Asymmetry of F1-ATPase Caused by the γ Subunit Generates a High Affinity Nucleotide Binding Site (*)
The α3β3γ and α3β3 complexes of F1-ATPase from a thermophilic Bacillus PS3 were compared in terms of interaction with… 
Highly Cited
1994
Highly Cited
1994
The three-dimensional structure of the ligand-binding domain of a wild-type bacterial chemotaxis receptor. Structural comparison to the cross-linked mutant forms and conformational changes upon…
The three-dimensional structures of the ligand-binding domain of the wild-type Salmonella typhimurium aspartate receptor have… 
Review
1990
Review
1990
Mapping of a cholinergic binding site by means of synthetic peptides, monoclonal antibodies, and alpha-bungarotoxin.
Previous studies by several laboratories have identified a narrow sequence region of the nicotinic acetylcholine receptor (AChR… 
Highly Cited
1988
Highly Cited
1988
The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case.
A weak Ca2+ binding site in the bacterial serine protease subtilisin BPN' (EC 3.4.21.14) was chosen as a model to explore the… 
Highly Cited
1983
Highly Cited
1983
Specific binding by human polymorphonuclear leucocytes of the immunological mediator 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine.
The binding of the platelet-activating factor 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphorylcholine (AGEPC) by human… 
Highly Cited
1981
Highly Cited
1981
The high affinity binding site on polyoma virus DNA for the viral large-T protein.
In order to map the high affinity binding site for the viral large-T protein on polyoma virus DNA, we have developed an assay… 
Highly Cited
1975
Highly Cited
1975
Carboxymethylation of horse-liver alcohol dehydrogenase in the crystalline state. The active-site zinc region and general anion-binding site of the enzyme correlated in primary and teritiary…
Horse liver alcohol dehydrogenase (isozyme EE) in the crystalline state was alkylated with iodoacetate under conditions resulting… 
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