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Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination,…
Abstract The complex formed by porcine pancreatic kallikrein A with the bovine pancreatic trypsin inhibitor (PTI) has been crystallized at pH 4 in tetragonal crystals of space group P 4 1 2 1 2 with… Expand
Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and…
- W. Bode, Z. Chen, K. Bartels, C. Kutzbach, G. Schmidt-Kastner, H. Bartunik
- Chemistry, Medicine
- Journal of molecular biology
- 1 February 1983
Abstract Porcine pancreas kallikrein A has been crystallized in the presence of the small inhibitor benzamidine, yielding tetragonal crystals of space group P 4 1 2 1 2 containing two molecules per… Expand
Recombinant rhizopuspepsinogen. Expression, purification, and activation properties of recombinant rhizopuspepsinogens.
- Z. Chen, G. Koelsch, +4 authors J. Tang
- Medicine, Chemistry
- The Journal of biological chemistry
- 25 June 1991
A cDNA clone, which contained the complete rhizopuspepsin structure and the putative proregion, was placed in three different Escherichia coli expression vectors for the synthesis of… Expand
Studies on pepsin mutagenesis and recombinant rhizopuspepsinogen.
- X. Lin, M. Fusek, +4 authors J. Tang
- Chemistry, Medicine
- Advances in experimental medicine and biology
During the past fifteen years, many chemical and three-dimensional structures of aspartic proteases have been determined. It is now clear that, in spite of some diverse substrate specificities, these… Expand
The X-ray structures of porcine pancreatic kallikrein and of its complex with bovine pancreatic trypsin inhibitor.
SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer prodrug with potent antitumor activity
3302 The pyrrolobenzodiazepines (PBDs) are a family of naturally occurring antitumor antibiotics. Many of the most potent family members contain a C2-endo-exo unsaturated motif associated with the… Expand
A Novel Approach to the Synthesis of Cytotoxic C2—C3 Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) with Conjugated Acrylyl C2-Substituents.
P152-M Mass Spectrometric Identification of Proteins of Purified Protein Derivative (PPD) of Mycobacterium Bovis Stain AN-5 Using a 2D HPLC Protein Fractionation System
Tuberculin PPD Bovis, Intradermic (purified protein derivative of Mycobacterium bovis strain AN-5) was widely used for the Tuberculin test in cattle. However, protein components of PPD remain unknown… Expand