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Beta-Arrestin-1, human

Known as: ARB1, Beta-Arrestin, Arrestin Beta-1 
Beta-arrestin-1 (418 aa, ~47 kDa) is encoded by the human ARRB1 gene. This protein plays a role in the desensitization of G-protein-coupled receptor… 
National Institutes of Health

Related topics

Related topics

16 relations
ARRB1 geneARRB1 wt AlleleCytoplasmEnzyme Inhibitor Protein

Broader (2)

beta-Arrestinsbeta-arrestin 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
Highly Cited
2006
Highly Cited
2006
Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
Adaptor protein complex 2 α and β-appendage domains act as hubs for the assembly of accessory protein networks involved in… 
Highly Cited
2003
Highly Cited
2003
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
Wnt proteins, regulators of development in many organisms, bind to seven transmembrane–spanning (7TMS) receptors called frizzleds… 
Highly Cited
2003
Highly Cited
2003
β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors
It is becoming increasingly clear that signaling via G protein-coupled receptors is a diverse phenomenon involving receptor… 
Highly Cited
2001
Highly Cited
2001
ARR1, a Transcription Factor for Genes Immediately Responsive to Cytokinins
Cytokinins are a class of phytohormones involved in various physiological events of plants. The Arabidopsis sensor histidine… 
Highly Cited
2000
Highly Cited
2000
Arabidopsis ARR1 and ARR2 response regulators operate as transcriptional activators.
The genes coding for the response regulators ARR1 and ARR2 have previously been identified by in silico screening of an… 
Highly Cited
1997
Highly Cited
1997
A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation*
G protein-coupled receptors (GPCR) represent the single most important drug targets for medical therapy, and information from… 
Highly Cited
1997
Highly Cited
1997
Arrestin/Clathrin Interaction
We have recently demonstrated that the nonvisual arrestins, β-arrestin and arrestin3, interact with high affinity and… 
Highly Cited
1995
Highly Cited
1995
Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
Persistent stimulation of the beta 1-adrenergic receptor (beta 1AR) engenders, within minutes, diminished responsiveness of the… 
Highly Cited
1992
Highly Cited
1992
Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.
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