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beta-arrestin 1

Known as: beta-Arrestin 1 [Chemical/Ingredient], Arrestin 2, ARRB1 Protein 
A beta-arrestin that functions in the down-regulation of signaling by G-PROTEIN-COUPLED RECEPTORS. It is also a major regulator of INSULIN signaling… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Besides their role in desensitization, beta-arrestin 1 and 2 promote the formation of signaling complexes allowing G protein… Expand
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Highly Cited
2008
Highly Cited
2008
GTP binding regulatory protein (G protein)-coupled receptors can activate MAPK pathways via G protein-dependent and -independent… Expand
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Highly Cited
2005
Highly Cited
2005
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine receptors are the best-established… Expand
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Highly Cited
2003
Highly Cited
2003
Stimulation of a mutant angiotensin type 1A receptor (DRY/AAY) with angiotensin II (Ang II) or of a wild-type receptor with an… Expand
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Highly Cited
2003
Highly Cited
2003
Stimulation of a mutant angiotensin type 1A receptor (DRY/AAY) with angiotensin II (Ang II) or of a wild-type receptor with an… Expand
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Highly Cited
2002
Highly Cited
2002
To permit direct functional analyses of neural circuits, we have developed a method for stimulating groups of genetically… Expand
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Highly Cited
2001
Highly Cited
2001
Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of β-arrestins in the… Expand
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Highly Cited
2001
Highly Cited
2001
The two widely coexpressed isoforms of beta-arrestin (termed beta arrestin 1 and 2) are highly similar in amino acid sequence… Expand
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Highly Cited
2000
Highly Cited
2000
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR… Expand
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Highly Cited
2000
Highly Cited
2000
Morphine is a powerful pain reliever, but also a potent inducer of tolerance and dependence. The development of opiate tolerance… Expand
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