beta-arrestin 1

Known as: beta-Arrestin 1 [Chemical/Ingredient], Arrestin 2, ARRB1 Protein 
A beta-arrestin that functions in the down-regulation of signaling by G-PROTEIN-COUPLED RECEPTORS. It is also a major regulator of INSULIN signaling… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
0102019932017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Insulin resistance, a hallmark of type 2 diabetes, is a defect of insulin in stimulating insulin receptor signalling, which has… (More)
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Highly Cited
2009
Highly Cited
2009
beta-Arrestins, originally discovered as terminators of G protein-coupled receptor signaling, have more recently been appreciated… (More)
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Highly Cited
2008
Highly Cited
2008
Visual and auditory hallucinations accompany certain neuropsychiatric disorders, such as schizophrenia, and they also can be… (More)
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Highly Cited
2007
Highly Cited
2007
The chemokine receptor CXCR4 is rapidly targeted for lysosomal degradation by the E3 ubiquitin ligase atrophin-interacting… (More)
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Highly Cited
2004
Highly Cited
2004
Many members of the chemokine receptor family of G protein-coupled receptors utilize multiple endogenous ligands. However… (More)
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Highly Cited
2004
Highly Cited
2004
Binding of Sonic Hedgehog (Shh) to Patched (Ptc) relieves the latter's tonic inhibition of Smoothened (Smo), a receptor that… (More)
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Highly Cited
2001
Highly Cited
2001
Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of beta-arrestins in the… (More)
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Highly Cited
2000
Highly Cited
2000
Morphine is a powerful pain reliever, but also a potent inducer of tolerance and dependence. The development of opiate tolerance… (More)
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Highly Cited
1995
Highly Cited
1995
Persistent stimulation of the beta 1-adrenergic receptor (beta 1AR) engenders, within minutes, diminished responsiveness of the… (More)
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Highly Cited
1994
Highly Cited
1994
The beta-adrenergic receptor system of the failing human heart is markedly desensitized. We have recently postulated that this… (More)
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