beta-Arrestins

Known as: beta Arrestins, beta-Arrestin, beta Arrestin 
Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They… (More)
National Institutes of Health

Papers overview

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Review
2006
Review
2006
Stimulation of cell-surface seven-transmembrane receptors (7TMRs) elicits biological responses to a wide range of extracellular… (More)
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Review
2005
Review
2005
The transmission of extracellular signals to the interior of the cell is a function of plasma membrane receptors, of which the… (More)
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Highly Cited
2005
Highly Cited
2005
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine receptors are the best-established… (More)
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Review
2002
Review
2002
beta-Arrestins are versatile adapter proteins that form complexes with most G-protein-coupled receptors (GPCRs) following agonist… (More)
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Highly Cited
2001
Highly Cited
2001
Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of beta-arrestins in the… (More)
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Highly Cited
2000
Highly Cited
2000
Morphine is a powerful pain reliever, but also a potent inducer of tolerance and dependence. The development of opiate tolerance… (More)
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Highly Cited
1999
Highly Cited
1999
The ability of morphine to alleviate pain is mediated through a heterotrimeric guanine nucleotide binding protein (G protein… (More)
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Highly Cited
1996
Highly Cited
1996
The ability of a system to regulate its responsiveness in the presence of a continuous stimulus, often termed desensitization… (More)
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Highly Cited
1996
Highly Cited
1996
beta-Arrestins are proteins that bind phosphorylated heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) and… (More)
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Highly Cited
1994
Highly Cited
1994
The beta-adrenergic receptor system of the failing human heart is markedly desensitized. We have recently postulated that this… (More)
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