Beta-Arrestin-1, human

Known as: ARB1, Beta-Arrestin, Arrestin Beta-1 
Beta-arrestin-1 (418 aa, ~47 kDa) is encoded by the human ARRB1 gene. This protein plays a role in the desensitization of G-protein-coupled receptor… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
A growing number of orphan G-protein-coupled receptors (GPCRs) have been reported to be activated by lipid ligands, such as… (More)
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Highly Cited
2006
Highly Cited
2006
Physiological effects of beta adrenergic receptor (beta2AR) stimulation have been classically shown to result from G(s)-dependent… (More)
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Highly Cited
2005
Highly Cited
2005
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine receptors are the best-established… (More)
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Review
2002
Review
2002
beta-Arrestins are versatile adapter proteins that form complexes with most G-protein-coupled receptors (GPCRs) following agonist… (More)
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Highly Cited
2001
Highly Cited
2001
Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of beta-arrestins in the… (More)
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Highly Cited
2000
Highly Cited
2000
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR… (More)
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Highly Cited
1999
Highly Cited
1999
The Ras-dependent activation of mitogen-activated protein (MAP) kinase pathways by many receptors coupled to heterotrimeric… (More)
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Highly Cited
1996
Highly Cited
1996
The ability of a system to regulate its responsiveness in the presence of a continuous stimulus, often termed desensitization… (More)
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Highly Cited
1996
Highly Cited
1996
The process of agonist-promoted internalization (sequestration) of G protein-coupled receptors (GPCRs) is intimately linked to… (More)
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Highly Cited
1996
Highly Cited
1996
beta-Arrestins are proteins that bind phosphorylated heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) and… (More)
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