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Beta-Arrestin-1, human

Known as: ARB1, Beta-Arrestin, Arrestin Beta-1 
Beta-arrestin-1 (418 aa, ~47 kDa) is encoded by the human ARRB1 gene. This protein plays a role in the desensitization of G-protein-coupled receptor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Endogenous mechanisms that act in the resolution of acute inflammation are essential for host defense and the return to… Expand
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Highly Cited
2006
Highly Cited
2006
Recent studies have shown that nicotine, a component of cigarette smoke, can stimulate the proliferation of non-neuronal cells… Expand
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Highly Cited
2005
Highly Cited
2005
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine receptors are the best-established… Expand
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Review
2002
Review
2002
beta-Arrestins are versatile adapter proteins that form complexes with most G-protein-coupled receptors (GPCRs) following agonist… Expand
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Highly Cited
2001
Highly Cited
2001
Using both confocal immunofluorescence microscopy and biochemical approaches, we have examined the role of β-arrestins in the… Expand
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Highly Cited
2000
Highly Cited
2000
Recently, a requirement for β-arrestin–mediated endocytosis in the activation of extracellular signal–regulated kinases 1 and 2… Expand
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Highly Cited
2000
Highly Cited
2000
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR… Expand
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Highly Cited
1998
Highly Cited
1998
The G protein-coupled mu-opioid receptor (mu OR) mediates the physiological effects of endogenous opioid peptides as well as the… Expand
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Highly Cited
1998
Highly Cited
1998
The classical paradigm for G protein-coupled receptor (GPCR) signal transduction involves the agonist-dependent interaction of… Expand
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Highly Cited
1996
Highly Cited
1996
β-Arrestins are proteins that bind phosphorylated heterotrimeric GTP-binding protein (G protein)-coupled receptors (GPCRs) and… Expand
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