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ARRB1 gene

Known as: ARRESTIN, BETA, 1, ARRB1, BETA-ARRESTIN 1 
This gene plays a role in signal transduction and is involved in neurotransmission.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Nicotine induces the proliferation of non-small cell lung cancer (NSCLC) cells via nicotinic acetylcholine receptors… Expand
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Highly Cited
2008
Highly Cited
2008
Since the unexpected discovery of the antipsychotic activity of chlorpromazine, a variety of therapeutic agents have been… Expand
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Highly Cited
2006
Highly Cited
2006
Deregulation of the Sonic hedgehog pathway has been implicated in an increasing number of human cancers. In this pathway, the… Expand
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Highly Cited
2005
Highly Cited
2005
Dopamine plays an important role in the etiology of schizophrenia, and D2 class dopamine receptors are the best-established… Expand
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Highly Cited
2005
Highly Cited
2005
The insulin-like growth factor-1 receptor (IGF-1R) plays important roles in physiological growth and aging as well as promoting… Expand
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Highly Cited
2003
Highly Cited
2003
Stimulation of a mutant angiotensin type 1A receptor (DRY/AAY) with angiotensin II (Ang II) or of a wild-type receptor with an… Expand
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Highly Cited
2002
Highly Cited
2002
The cellular localization, agonist-mediated internalization, and desensitization properties of the alpha(1)-adrenoceptor (alpha(1… Expand
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Highly Cited
2000
Highly Cited
2000
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR… Expand
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Highly Cited
1999
Highly Cited
1999
The ability of morphine to alleviate pain is mediated through a heterotrimeric guanine nucleotide binding protein (G protein… Expand
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Highly Cited
1993
Highly Cited
1993
Arrestins have been implicated in the regulation of many G protein-coupled receptor signaling cascades. Mutations in two… Expand
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