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ARRB1 gene

Known as: ARRESTIN, BETA, 1, ARRB1, BETA-ARRESTIN 1 
This gene plays a role in signal transduction and is involved in neurotransmission.
National Institutes of Health

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ARRB1 wt Allele
Beta-Arrestin-1, humanSignal Transductionbeta-arrestin 1

Papers overview

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2010
2010
Overexpression of beta-arrestin 2 in peripheral blood mononuclear cells of patients with cryptococcal meningitis.
Cryptococcal meningitis is often associated with elevated IL-10 levels, which suggest a dysregulation in the antifungal immune… 
2009
2009
Obestatin stimulates Akt signalling in gastric cancer cells through beta-arrestin-mediated epidermal growth factor receptor transactivation.
Obestatin was identified as a gut peptide encoded by the ghrelin gene that interacts with the G protein-coupled receptor, GPR39… 
2009
2009
Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival.
Highly Cited
2007
Highly Cited
2007
Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1.
CD4+ T cells are important in adaptive immunity, but their dysregulation can cause autoimmunity. Here we demonstrate that the… 
2006
2006
The human thyrotropin receptor is predominantly internalized by beta-arrestin 2.
The beta-arrestin-dependent endocytosis of the beta2-adrenergic receptor (beta2AR) has been demonstrated by confocal fluorescence… 
2006
2006
Decreased morphine analgesia in rat overexpressing β-arrestin 2 at periaqueductal gray
2006
2006
Beta-arrestin 2 modulates the activity of nuclear receptor RAR beta2 through activation of ERK2 kinase.
The activity of retinoid receptors activity can be regulated by various extracellular stimuli. In an effort to understand the… 
Highly Cited
2002
Highly Cited
2002
Homo- and Hetero-oligomerization of Thyrotropin-releasing Hormone (TRH) Receptor Subtypes
G-protein-coupled receptors (GPCRs) are regulated by a complex network of mechanisms such as oligomerization and internalization… 
1994
1994
Mechanism of arrestin 2 function in rhabdomeric photoreceptors.
1994
1994
Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes.
Two types of proteins play a major role in determining homologous desensitization of G-coupled receptors: beta-adrenergic… 
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