Benzo[a]pyrene trans-7,8-Dihydrodiol

Known as: benzo(a)pyrene 7,8-dihydrodiol, (trans)-isomer, BPD, trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene 
A polycyclic aromatic hydrocarbon and metabolite of benzo(a)pyrene with potent cytotoxic and mutagenic properties. Benzo(a)pyrene-trans-7,8… (More)
National Institutes of Health

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2014
2014
Lung cancer is the leading cause of cancer deaths and remains an important public health problem worldwide. Long noncoding RNAs… (More)
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2011
2011
Growing evidence indicates that the alteration of microRNA (miRNA) expression in tumors that is induced by chemical carcinogens… (More)
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2010
2010
Shorter telomere length (TL) in peripheral blood lymphocytes (PBLs) is predictive of lung cancer risk. Polycyclic aromatic… (More)
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2009
2009
In the accompanying report (p. 1031), we showed that a novel dioxin-inducible cytochrome P450, CYP2S1, efficiently metabolizes… (More)
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2006
2006
Interindividual differences in DNA repair capacity (DRC) may play a critical role in breast cancer risk. Previously, we… (More)
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2004
2004
Metabolism of the environmental pollutant benzo[a]pyrene in the bacterium Mycobacterium vanbaalenii PYR-1 was examined. This… (More)
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1994
1994
Cytochrome P450 1A1 (CYP1A1) activity is associated with increased susceptibility to lung cancer induced by polycyclic aromatic… (More)
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Highly Cited
1989
Highly Cited
1989
A total of 57 procarcinogens was examined for induction of umu gene response in the chimeric plasmid pSK1002, carried in… (More)
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Highly Cited
1978
Highly Cited
1978
The tumorigenicities of benzo[a]pyrene and each optical enantiomer of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides… (More)
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