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Benzo[a]pyrene trans-7,8-Dihydrodiol

Known as: benzo(a)pyrene 7,8-dihydrodiol, (trans)-isomer, BPD, trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene 
A polycyclic aromatic hydrocarbon and metabolite of benzo(a)pyrene with potent cytotoxic and mutagenic properties. Benzo(a)pyrene-trans-7,8… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Polycyclic aromatic hydrocarbons (PAHs) are known to induce reactive oxygen species and oxidative stress, but the dose-response… Expand
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2011
2011
Growing evidence indicates that the alteration of microRNA (miRNA) expression in tumors that is induced by chemical carcinogens… Expand
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Highly Cited
2010
Highly Cited
2010
Shorter telomere length (TL) in peripheral blood lymphocytes (PBLs) is predictive of lung cancer risk. Polycyclic aromatic… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Interindividual differences in DNA repair capacity may influence cancer risk. We tested whether the nucleotide… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Metabolism of the environmental pollutant benzo[a]pyrene in the bacterium Mycobacterium vanbaalenii PYR-1 was examined… Expand
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Highly Cited
2000
Highly Cited
2000
DNA lesion bypass is an important cellular response to genomic damage during replication. Human DNA polymerase eta (Pol(eta… Expand
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Highly Cited
1997
Highly Cited
1997
A mouse embryo culture model was used to determine whether embryonic prostaglandin H synthase (PHS)-catalyzed bioactivation and… Expand
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Highly Cited
1994
Highly Cited
1994
Humans are exposed to polycyclic aromatic hydrocarbons (PAHs) from various occupational, environmental, medicinal and dietary… Expand
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Highly Cited
1989
Highly Cited
1989
A total of 57 procarcinogens was examined for induction of umu gene response in the chimeric plasmid pSK1002, carried in… Expand
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Highly Cited
1983
Highly Cited
1983
Cultured bronchial epithelial and fibroblastic cells from humans were used to study DNA damage and toxicity caused by… Expand
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