Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbons.

@article{Pavanello2010ShorterTL,
  title={Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbons.},
  author={Sofia Pavanello and A Pesatori and Laura Dioni and Mirjam Hoxha and Valentina Bollati and Ewa Siwińska and Danuta Mielzyńska and Claudia Bolognesi and Pier-Alberto Bertazzi and Andrea A. Baccarelli},
  journal={Carcinogenesis},
  year={2010},
  volume={31 2},
  pages={216-21}
}
Shorter telomere length (TL) in peripheral blood lymphocytes (PBLs) is predictive of lung cancer risk. Polycyclic aromatic hydrocarbons (PAHs) are established lung carcinogens that cause chromosome instability. Whether PAH exposure and its molecular effects are linked with shorter TL has never been evaluated. In the present study, we investigated the effect of chronic exposure to PAHs on TL measured in PBLs of Polish male non-current smoking cokeoven workers and matched controls. PAH exposure… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 46 references

Genetic variation in telomere maintenance genes , telomere length , and lung cancer susceptibility

K. Woodson
2009

Telomere length and gastric cancer risk

K. Nordfjäll
Cancer Epidemiol . Biomarkers Prev . • 2009

Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis , nickel , arsenic , and chromium

M. Esteller
Chem . Res . Toxicol . • 2008

Lung cancer epigenetics and genetics

I. P. Pogribny
Int . J . Cancer • 2008

Micronuclei related to anti-B[a]PDE-DNA adduct in peripheral blood lymphocytes of heavily polycyclic aromatic hydrocarbon-exposed nonsmoking coke-oven workers and controls.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2008

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