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BW-755C

Known as: BW 755C, BW755C 
National Institutes of Health

Papers overview

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Highly Cited
1990
Highly Cited
1990
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in α‐adrenoceptor responsiveness with age and disease in isolated tissues
1 The pathophysiology of impotence related to vascular smooth muscle dysfunction in the male corpus cavernosum was studied on… 
Highly Cited
1988
Highly Cited
1988
The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis. Serial clinical, electrophysiological, biochemical and morphological observations.
Experimental allergic neuritis (EAN) can be prevented or ameliorated by global blockade of macrophages. How these cells damage… 
Highly Cited
1986
Highly Cited
1986
Identification of distinct activation pathways of the human neutrophil NADPH-oxidase.
The stimulation of the human neutrophil NADPH-oxidase is initiated by a variety of agonists, which appear to utilize more than… 
Highly Cited
1984
Highly Cited
1984
Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets.
Highly Cited
1984
Highly Cited
1984
The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
Highly Cited
1983
Highly Cited
1983
The effects of BW755C and other anti‐inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally‐induced acute inflammation
BW755C (3‐amino‐1‐[m‐trifluoromethyl)phenyl]‐2‐pyrazoline HCl) reduced the concentration of leukotriene B4 (LTB4), thromboxane B2… 
Highly Cited
1983
Highly Cited
1983
Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa.
The human colon synthetises several prostanoids which may have a role in inflammatory bowel diseases. As lipoxygenase products of… 
Highly Cited
1982
Highly Cited
1982
Role of arachidonate metabolism in the immunoregulatory function of human leukocytic pyrogen/lymphocyte-activating factor/interleukin 1.
Highly Cited
1980
Highly Cited
1980
The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation.
Highly Cited
1979
Highly Cited
1979
A new approach to anti-inflammatory drugs.
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