Skip to search formSkip to main contentSkip to account menu

Ansamycins

Known as: Ansamycin Antibiotics, Ansamycin Antineoplastic Antibiotic, ansamycin 
An antineoplastic antibiotic of macrocyclic benzoquinone isolated from the bacterial genus Streptomyces. Ansamycin antibiotics bind to and inhibit… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Lactams, Macrocyclic

Narrower (2)

MycobutinRifabutin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Two herbimycin analogs, 4,5-dihydro-(4S)-4-hydroxyherbimycin B and (15S)-15-hydroxyherbimycin B, from Streptomyces sp. CPCC 200291
Two herbimycin analogs, 4,5-dihydro-(4 S )-4-hydroxyherbimycin B and (15 S )-15-hydroxyherbimycin B, from Streptomyces sp. CPCC… 
1986
1986
Antimycobacterial activities of two newer ansamycins, R-76-1 and DL 473.
: The antimycobacterial activities of two newer ansamycins, isobutylpiperazinylrifamycin SV (R-76-1) and cyclopentylrifamycin SV… 
1985
1985
Studies on mycotrienin antibiotics, a novel class of ansamycins. V. Isolation and structure determination of novel mycotrienin congeners.
ponents, mycotrienols I and II1). Independently, ZEECK et a!. isolated closely related compounds named ansatrienins A and B… 
1985
1985
Chemical modifications of the aliphatic bridge of ansamycins. 3. Synthesis and activity of 21-epi-rifamycin S.
Rifamycins inhibit bacterial DNA-dependent RNA polymerase through the formation of non-covalent bonds by the oxygenated groups at… 
1983
1983
Chemical modifications of the aliphatic bridge of ansamycins. Synthesis and activity of 25-deacetoxy-25-epi-hydroxyrifamycin S.
Rifamycins are supposed to bind to, and inhibit the bacterial DNA-dependent RNA polymerase (DDRP) by the formation of hydrogen… 
1983
1983
MIC values do not predict the intraphagocytic killing of Staphylococcus aureus by naphthalenic ansamycins.
Ten naphthalenic ansamycins were compared for their ability to kill extracellular or phagocytosed Staphylococcus aureus 502A… 
1980
1980
Early intermediates in the biosynthesis of ansamycins. III. Isolation and identification of further 8-deoxyansamycins of the rifamycin-type.
A number of minor compounds were isolated from fermentations of the protorifamycin I producing strain Nocardia mediterranei F 1… 
1977
1977
Synthesis and antibacterial activity of some derivatives of tolypomycinone. Relationship between structure and activity in ansamycins.
3-Aminotolypomycinoes and 3,16-diamino-16,17-dihydrotolypomycinones are formed by the addition of primary and secondary amines to… 
Review
1975
Review
1975
Rifamycins and Other Ansamycins
The various actions of the rifamycins have been reviewed recently by the authors (Wehrli and Staehelin, 1971). The antimicrobial… 
1974
1974
Ansamycin biogenesis: studies on a novel rifamycin isolated from a mutant strain of Nocardia mediterranei.
A novel ansamycin, rifamycin W, was isolated from a mutant strain of Nocardia mediterranei. The metabolic origin of rifamycin W…