Houseflies: not simple mechanical vectors of enterohemorrhagic Escherichia coli O157:H7.
- M. Kobayashi, T. Sasaki, N. Agui
- MedicineAmerican Journal of Tropical Medicine and Hygiene
- 1 October 1999
Feeding experiments of EHEC-O157 to houseflies showed that the ingested bacteria were harbored in the intestine of flies and continued to be excreted at least for 3 days after feeding, strongly suggesting that houseflies are not simple mechanical vectors of EhEC.
A new anthelmintic cyclodepsipeptide, PF1022A.
- T. Sasaki, M. Takagi, T. Yaguchi, S. Miyadoh, T. Okada, M. Koyama
- Biology, MedicineJournal of antibiotics (Tokyo. )
- 25 May 1992
The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It showed strong anthelmintic activities against Ascaridia galli in…
TPU-0031-A and B, new antibiotics of the novobiocin group produced by Streptomyces sp. TP-A0556.
- T. Sasaki, Y. Igarashi, N. Saito, T. Furumai
- Biology, ChemistryJournal of antibiotics (Tokyo. )
- 25 May 2001
Two novel antibiotics, TPU-0031-A and B, were isolated from the culture broth of an actinomycete strain and showed antibiotic activity against Gram-positive and -negative bacteria.
A new tetracycline antibiotic with antitumor activity. I. Taxonomy and fermentation of the producing strain, isolation and characterization of SF2575.
It was active against Gram-positive bacteria and exhibited antitumor activity against P388 leukemia in mice and revealed to be a new tetracycline antibiotic.
Marine natural products. XXXII. Absolute configurations of C-4 of the manoalide family, biologically active sesterterpenes from the marine sponge Hyrtios erecta.
- M. Kobayashi, T. Okamoto, K. Hayashi, N. Yokoyama, T. Sasaki, I. Kitagawa
- Chemistry, BiologyChemical and pharmaceutical bulletin
Manoalide 25-acetals were shown to exhibit in vivo antitumor activity and to inhibit theDNA-relaxing activity of mouse DNA topoisomerase I and the DNA-unknotting activity of calf thymus DNA top Loisomerase II.
Agelasine G, a new antileukemic alkaloid from the Okinawan marine sponge Agelas sp.
- K. Ishida, M. Ishibashi, H. Shigemori, T. Sasaki, J. Kobayashi
- ChemistryChemical and pharmaceutical bulletin
- 25 March 1992
A new antileukemic alkaloid, agelasine G (1a), has been isolated from the Okinawan marine sponge Agelas sp. and its structure elucidated to be a bromopyrrole alkaloid containing 9-methyladenine and…
Niphatesines E–H, new pyridine alkaloids from the Okinawan marine sponge Niphates sp.
Four new mono-3-alkyl-substituted pyridine alkaloids, niphatesines E–H (1–4), possessing oxime methyl ether or methoxyamine functionality have been isolated from the Okinawan marine sponge Niphates…
Cystodytins D-I, new cytotoxic tetracyclic aromatic alkaloids from the Okinawan marine tunicate Cystodytes dellechiajei.
Brasilicardin A. A Novel Tricyclic Metabolite with Potent Immunosuppressive Activity from Actinomycete Nocardia brasiliensis
SF2487, a new polyether antibiotic produced by Actinomadura.
The antibiotic represents a new member of polyether group antibiotics known as the acyltetronic acid type 4 and is weakly active against Gram-positive bacteria and exhibits antiviral activity against influenza virus in vitro.