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Anisomycin

Known as: 3,4-Pyrrolidinediol, 2-((4-methoxyphenyl)methyl)-, 3-acetate, (2R-(2alpha,3alpha,4beta))-, Anisomycin [Chemical/Ingredient], (-)-Anisomycin 
An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (4)

Anti-Bacterial AgentsAntiprotozoal AgentsNucleic Acid Synthesis InhibitorsProtein Synthesis Inhibitors

Narrower (3)

Flagecidinpreussinpreussin B
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2
Studies on various forms of synaptic plasticity have shown a link between messenger RNA translation, learning and memory. Like… 
Highly Cited
2003
Highly Cited
2003
Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit.
Highly Cited
2001
Highly Cited
2001
Dynamic Visualization of Local Protein Synthesis in Hippocampal Neurons
Highly Cited
1993
Highly Cited
1993
Taste memory: the role of protein synthesis in gustatory cortex.
Highly Cited
1991
Highly Cited
1991
Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors
Highly Cited
1989
Highly Cited
1989
Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization
Highly Cited
1988
Highly Cited
1988
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
We have developed an experimental paradigm to study the mechanism by which nerve growth factor (NGF) allows the survival of… 
Highly Cited
1988
Highly Cited
1988
Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
Highly Cited
1976
Highly Cited
1976
The induction of ornithine decarboxylase as an early, possibly obligatory, event in mouse skin carcinogenesis.
Summary A single, topical application of croton oil or its active component, 12-O-tetracanoyl-phorbol-13-acetate (TPA), results… 
Highly Cited
1970
Highly Cited
1970
Structure and function of mammalian ribosomes. I. Isolation and characterization of active liver ribosomal subunits.
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